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Microfilm tablet press

　　Microfilm: the diameter is between 1-3mm, the content is uniform and the quality is controllable.

　　Diameter comparison between microchip and ordinary microchip.

　　The "microchip" medicine specially designed for children is small in size and easy to swallow.

Orally disintegrating tablets freeze-dried orally disintegrating tablets

　　"Freeze-dried orally disintegrating tablets" will immediately disperse in the mouth to prevent spitting.

　　Adults all know the truth that "good medicine tastes bitter and is good for disease", but for children, bitter medicine is unwilling to take even if it has a curative effect. In the future, in children’s medication, the bitter taste of good medicine may become history.

　　The pills will be made into cute little bears or cute kittens. Bitter potion adds sweet and sour "flavoring agent", which has strawberry flavor and orange flavor, depending on which one the baby likes; Naughty children will spit out after eating pills. After changing to "freeze-dried orally disintegrating tablets", the pills will spread on the tongue and disappear, and they can’t find pills when they want to vomit … …

　　The National Children’s Medical Center and Beijing Children’s Hospital affiliated to Capital Medical University, as the lead units, joined forces with the R&D forces of more than 30 scientific research institutes, universities and enterprises across the country to start the research and development of drug varieties and key technologies for children, which is also the 2017 project of the "Thirteenth Five-Year Plan" national "major new drug creation" and will be closed at the end of next year.

　　Ni Xin, the project leader and president of Beijing Children’s Hospital, said that the related technology of this project involves more than 100 kinds of children’s medicines. In the future, good medicines will no longer be bitter, and children will no longer need parents and children to "fight with each other".

　　decode

　　Oral medicine is too bitter

　　By the end of next year, a technical platform for correcting and masking the taste of children’s drugs will be built.

　　"One thing touched me deeply." Wang Xiaoling, director of the project office and director of the pharmacy department of Beijing Children’s Hospital, said that a child in the hospital was ill and had to take a sugar-coated tablet for adults. Because the dosage of the child was small, the sugar-coated tablet could only be ground and then fed to the child. "Once the sugar-coated tablet is destroyed, the bitter taste in the medicine will go straight to the entrance." The child was particularly angry and said, Why do adults take sweet medicine, but give me such bitter medicine? How can you adults be so bad! "This sentence makes me particularly shocked. Why can’t we adults try to make our children’s medicine no longer bitter?"

　　The child can’t understand the helplessness behind grinding a sugar-coated tablet and taking it again. His idea is very simple, that is, he wants to take medicine that is not bitter. Wang Xiaoling said that as one of the top ten tasks of the project, China will build a technical platform for correcting and masking the taste of children’s drugs by the end of next year. The specific technical types of taste correction and taste masking for children include taste masking technology, chemical taste masking technology and physical taste masking technology. "Some medicines are naturally bitter." Like other tastes, bitterness is a feeling caused by the stimulation of liquid containing chemical substances. Bitter substances existing in food and medicine basically naturally exist alkaloids, glycosides, bitter peptide bile and other substances, and some nitrogen-containing organic substances can also have a bitter feeling.

　　"We have established a bitterness database." Wang Xiaoling said that in the future, when children’s drug manufacturers develop new drugs, they can query the database and consider avoiding these bitter ingredients. However, the first thing to consider in drug research and development is curative effect. If bitter chemicals cannot be avoided, it is necessary to consider improving the taste of children’s drugs through taste correction technology or taste masking technology. "Just like giving people a double eyelid, beautify it."

　　The technology of taste masking and taste correction seems to be relatively uncommon, but in simple terms, it can be understood as the illusion of baby’s taste buds by adding "condiments"; It is also possible to avoid direct contact between bitter drugs and taste buds by adding auxiliary materials, or to temporarily paralyze taste buds. Now many babies have taken medicines that are not bitter, such as peaches, strawberries, oranges, hawthorn, milk tea and brown sugar … … Wang Xiaoling said that before the end of next year, the research group will also build a taste evaluation system for children in China. "Now many taste masking and taste correction technologies are imported. We should choose a taste that is more suitable for children in China according to the tastes of children in China."

　　The taste of children’s medication is not just "not bitter". Wang Xiaoling said that the waterless swallowing granule technology currently under development adopts technological innovation and high-quality auxiliary materials, which can effectively cover up the bad smell of drugs, and at the same time, it does not need water to be taken. After entering the stomach, the drugs are quickly dissolved and released, giving full play to the curative effect, greatly improving the compliance of children with drugs, and parents are no longer worried about the headache of drug administration.

　　decode

　　Dose is broken by hand

　　Customize different dosage packages for babies with professional packaging equipment.

　　In the young children’s ward of Beijing Children’s Hospital, pharmacists also have an important job of grinding pills for children. Hydrochlorothiazide, a commonly used medicine in children’s wards, is used to treat mild and moderate edema and hypertension, and can improve the symptoms of bronchial dysplasia. In the children’s ward, this is a drug that challenges pharmacists: the commonly used hydrochlorothiazide tablets are 25 mg per tablet, but the dosage of children needs to be calculated according to their weight. Some children need to use one-third tablets, and some children need to use one-quarter tablets. The youngest child needs to use 0.5 mg at a time, which is only 1/50 of one tablet. "Ordinary scales can’t be used for weighing, and analytical scales with higher accuracy must be used."

　　In the ward of Beijing Children’s Hospital, there are many commonly used divided-dose drugs. Compound sulfamethoxazole tablets are used to treat enteritis, endocarditis, acute bronchitis and chronic bronchitis in children’s hospitals, and are likely to be used in the departments of gastroenterology, cardiovascular medicine, respiratory medicine, neurology and infectious diseases. 79.95% of the compound sulfamethoxazole tablets used in children’s hospitals need to be divided into doses. Among the 199 kinds of oral drugs available in Beijing Children’s Hospital, 85 kinds of drugs, such as oral liquid, granules, dispersible tablets, etc., and 34 kinds of drugs with different doses, are excluded, and a total of 80 kinds of drugs need to be prepared in different doses, including 63 kinds of tablets and 12 kinds of capsules, as well as dosage forms such as enteric-coated tablets and sustained-release tablets.

　　According to the drug classification of clinical medication instructions, most of these 80 drugs are used for anti-infective drugs, nervous system, cardiovascular system, digestive system and endocrine system. Infection and digestive diseases are very common in children, and many children will use these drugs. Cardiovascular, endocrine and nervous system drugs sometimes need long-term out-of-hospital drug treatment. If there is no suitable dosage form specification and parents need to divide the dosage themselves, how to ensure the accurate dosage of drugs? How to ensure the proper storage of divided dose drugs? How to deal with the remaining drugs after dispensing? Is it necessary to buy an analytical balance specially for children to distribute medicine at home?

　　In some developed countries, such as Japan, personalized drug delivery has begun, which means that hospitals can use special equipment to package drugs separately. In China’s "Quality Management Standard for Pharmaceutical Work in Medical Institutions", there is also a clear definition of individualized dispensing — — According to the needs of patients’ individualized medication, qualified medical institutions can provide temporary preparation of special dosage forms or doses, such as diluting liquid, grinding tablets and subcontracting, subpackaging capsules, preparing temporary mixtures, and preparing ointments.

　　This year, the topic of personalized medication for young children has been added. At present, the research group has purchased sub-packaging equipment. In the future, Beijing Children’s Hospital can customize drugs with special doses for babies. "The content of a bag may be 10 micrograms or 5 milligrams, which can be designed completely according to the doctor’s advice. Parents give their children medicine, and they don’t have to guess. "

　　decode

　　It is difficult to swallow medicine.

　　Develop special formula technology

　　Develop special drugs for children

　　The problem of children’s medication is a worldwide topic. "We often say that children are not miniature versions of adults." Ni Xin said that children should choose special drugs for children. The project led by Beijing Children’s Hospital is based on the differentiated needs of children’s medication, developing special drug delivery technologies, including straw delivery, oral instant, micro-tablets, etc., and developing children’s drugs through the establishment of key technologies with distinctive differentiation.

　　For example, Wang Xiaoling said that according to the characteristics of children, the research group is still developing "microchips", that is, the diameter of tablets is between 1 and 3 mm, "too big tablets for children to swallow." After being changed into small tablets, the diameter is reduced to facilitate swallowing, and more importantly, the content of active ingredients in the medicine is uniform and the quality is controllable. Now adults are using sustained-release tablets, and the drugs can be released slowly. Adults can take the drugs once or twice a day. Children have to go to kindergarten and primary school, but many children need to take drugs orally three or even four times a day. This time, the research group also designed the sub-topic of key technology and industrialization platform of children’s sustained and controlled release preparations to explore and develop sustained and controlled release preparations suitable for children, and studied the oral absorption mechanism.

　　Children take drugs orally and through mucous membranes, such as nasal mucosa, rectal mucosa and lung mucosa, all of which are routes of administration. "The World Health Organization recommends that children use anal suppositories to reduce fever, but parents in China don’t accept it very well and children don’t like it." Wang Xiaoling said, this suggests that Chinese researchers can’t copy foreign experience. "We found that the gel dosage form is relatively easy to be accepted by parents, and the products developed now are highly accepted by parents. If you gently touch it, you can achieve good curative effect, and parents certainly welcome it. "

　　"Nothing reveals the soul of a society better than the way it treats its children." Wang Xiaoling always remembers such a famous saying, "All pharmaceutical workers do is to make children recover in sweetness."

　　Reporter Jia Xiaohong

　　On April 3rd, the education conference on studying and implementing the theme of Socialism with Chinese characteristics Thought of the Supreme Leader in the new era was held in Beijing. General Secretary of the Supreme Leader attended the conference and delivered an important speech. From the strategic height of the overall development of the cause of the party and the country in the new era and new journey, the important speech of the Supreme Leader General Secretary profoundly expounded the great significance and target requirements of carrying out theme education, made comprehensive arrangements for all the work of theme education, and provided fundamental follow-up for the whole party to carry out theme education. Based on the spirit of the important speech delivered by the Supreme Leader General Secretary at the theme education work conference, this paper will analyze and explain why theme education should be carried out and its purpose and practice.

　　First, attaching importance to theoretical arms is an important experience for Marxist political parties to win.

　　Why should we carry out thematic education? This issue needs to be understood from the nature of our party and its experience.

　　Marxism holds that the birth of proletarian political parties is the key to the transformation of the proletariat from spontaneous to conscious. Organizationally, through the establishment of proletarian political parties, the proletariat has its own political organization, so that the proletariat can be organized. Ideologically, through the propaganda of proletarian political parties, Marxist theory can be spread among the proletariat and the proletariat can realize its mission. Therefore, Marxism has promoted the formation of highly conscious and organized actors through the organization and propaganda of political parties, so that ideological theory can be transformed into action force and practical results.

　　Therefore, after the establishment of the Communist Party of China (CPC), it has continuously promoted the modernization of Marxism in China, and through organization, mobilization, publicity and education, the whole party and the people of the whole country have mastered scientific theories and cognitive tools, made clear the historical mission and central tasks, and made clear the line, principles and specific policies. Among them, party member, especially the party’s leading cadres, is required to systematically master Marxist theory and the party’s line, principles and policies, so as to lay a theoretical foundation and provide capacity guarantee for the party to assume leadership responsibilities, thus becoming one of the important experiences for our party to win in each historical period.

　　Therefore, the cadre education in party member has become an important basic work of Party building, and it has been promoted through the combination of daily education and centralized education. Among them, centralized education is divided into two ways: one is to send party member cadres to Party schools for systematic training, and the other is to focus on a certain topic for a period of time to carry out education throughout the Party.

　　As an activity of a political organization, inner-party learning is for application and inner-party education is for practice. Therefore, every time we carry out theme education, our party attaches importance to both theoretical learning and practical transformation. Through systematic theoretical study, the theoretical level of all party member and cadres will be promoted to a higher level, and through targeted practice transformation, the achievements of the modernization of Marxism in China will be continuously transformed into the action force of party member cadres, and a certain key issue within the Party will be solved.

　　Second, the completion of the new era, new journey, mission and task requires the guidance and arms of the party’s innovative theory.

　　After understanding why our party should carry out theme education, the next question is: "Why is this theme education to study and implement Socialism with Chinese characteristics Thought of the Supreme Leader in the New Era?" To answer this question, we need to grasp it from the historical logic, theoretical logic and practical logic of socialist modernization and the modernization of Marxism in China.

　　After the Opium War, the Chinese nation suffered an unprecedented disaster. After arduous exploration by countless people with lofty ideals, the people of China chose the Communist Party of China (CPC) as the leading force and Marxism as the guiding ideology. Under the leadership of the Communist Party of China, under the guidance of Marxism and through the efforts of the people of China, we have completed the central task of each historical period, achieved the goal of the first century, and started a new journey of comprehensively promoting the great rejuvenation of the Chinese nation with Chinese modernization.

　　Our great cause was achieved under the guidance of Marxism, and an important experience of our victory is to constantly promote the modernization of Marxism in China. Through the combination of the basic principles of Marxism with China’s concrete practice and Chinese excellent traditional culture, we will constantly enrich Marxism with China’s experience in revolution, construction and reform, so that it can effectively guide China’s practice at every stage. In the process of revolution, construction and reform, and in the process of promoting the modernization of Marxism in China, our party formed Mao Zedong Thought, Deng Xiaoping Theory, Theory of Three Represents and Scientific Outlook on Development.

　　With Socialism with Chinese characteristics entering a new era, under the leadership of the CPC Central Committee with the Supreme Leader as the core, we have carried out great struggles with many new historical characteristics, made great achievements and great changes in the new era for ten years, opened up a new realm of the modernization of Marxism in China, and formed Socialism with Chinese characteristics Thought of the Supreme Leader in the new era, a contemporary China Marxism and a 21st century Marxism.

　　With the completion of the goal of the first century, "from now on, the central task of the Communist Party of China (CPC) is to unite and lead the people of all ethnic groups in the country to build a socialist modernization power in an all-round way, realize the goal of the second century, and comprehensively promote the great rejuvenation of the Chinese nation with Chinese modernization." According to the successful experience of our party, to successfully complete the mission of the new journey, we must arm the whole party with Socialism with Chinese characteristics Thought of the Supreme Leader in the New Era, which is the latest achievement of the modernization of Marxism in China. Therefore, it is necessary to carry out the theme education of studying and implementing Socialism with Chinese characteristics Thought of the Supreme Leader in the New Era.

　　As General Secretary of the Supreme Leader pointed out, "The grand goal of building a strong country and national rejuvenation is inspiring and inspiring, and our generation of communist party people has a glorious mission and a great responsibility. We should take this theme education as an opportunity to strengthen the party’s innovative theory, constantly improve the Marxist level of the whole party, continuously improve the party’s ruling ability and leadership level, gather together for the new journey of forging ahead, work hard and courageously, and unite and struggle for building a socialist modern country in an all-round way and comprehensively promoting the great rejuvenation of the Chinese nation. "

　　Third, the theme education is an important means to transform the Supreme Leader’s Socialism with Chinese characteristics Thought into a powerful force in the new era.

　　When we understand "why this theme education is to study and implement Socialism with Chinese characteristics Thought of the Supreme Leader in the New Era", we must also know what is the fundamental task of this theme education?

　　At the conference on studying and implementing the theme education of Supreme Leader Socialism with Chinese characteristics Thought in the new era, General Secretary of Supreme Leader gave a clear answer, that is, "To carry out this theme education, the fundamental task is to adhere to the integration of learning, thinking and application, and to unify knowledge, belief and practice, and to transform Socialism with Chinese characteristics Thought in the new era into a powerful force to strengthen ideals, temper party spirit, guide practice and promote work, so that the whole party can always maintain a unified thought, firm will, coordinated actions and strong combat effectiveness, and strive to build souls through learning and increase their strength through learning. While pointing out the fundamental task of this theme education, the General Secretary of the Supreme Leader particularly emphasized that this theme education should achieve "five essentials", namely, to build a solid foundation with a firm heart, to temper character, to strengthen loyalty, to work hard to promote development, to practice the purpose of benefiting the people, and to establish a new atmosphere of honesty and integrity.

　　After understanding the fundamental task of this theme education, we can draw the following conclusions: It is an important means to transform Socialism with Chinese characteristics Thought of the Supreme Leader in the new era into a powerful force by focusing on leading cadres at or above the county level, and it is also an important measure to implement the spirit of the 20th Party Congress, which is of great significance for unifying the Party’s thinking, solving outstanding problems within the Party, maintaining the flesh-and-blood ties between the Party and the people, and promoting the development of the cause of the Party and the country.

　　Fourth, the theme education should firmly grasp the general requirements of "learning ideas, strengthening party spirit, emphasizing practice and making new contributions"

　　The next important question is, how should this theme education be carried out?

　　At the work conference on studying and implementing the theme education of Socialism with Chinese characteristics Thought in the new era of the Supreme Leader, the General Secretary of the Supreme Leader emphasized that this theme education should firmly grasp the general requirements of "learning ideas, strengthening party spirit, emphasizing practice and making new contributions". First, we should comprehensively study and understand Socialism with Chinese characteristics Thought in the new era; second, we should consciously transform the subjective world with Socialism with Chinese characteristics Thought in the new era; third, we should consciously practice Socialism with Chinese characteristics Thought in the new era; fourth, we should learn the wisdom and strength to forge ahead from Socialism with Chinese characteristics Thought in the new era.

　　With regard to specific steps and practices, General Secretary of the Supreme Leader emphasized that this theme education should be integrated with theoretical study, investigation and research, promotion of development, inspection and rectification, and promoted organically and integrally. Of course, in practical work, we must also pay attention to the targeted work of establishing rules and regulations in order to be able to form a normalization effect on the achievements of this theme education. As this theme education is a major event that has a bearing on the overall situation, the time is tight, the task is heavy and the requirements are high. To this end, the General Secretary of the Supreme Leader requires party committees (party groups) at all levels to shoulder the main responsibility and plan, organize and implement the theme education well. (The author is the director of the Research Center for Party Building and National Development of Fudan University, a think tank of Shanghai universities, and a professor at the School of International Relations and Public Affairs of Fudan University.)

　　April 15th to 21st is the 25th National Cancer Prevention Publicity Week, and this year’s publicity theme is "Scientific Cancer Prevention First".

　　Cancer, also known as malignant tumor, is a complex disease caused by social and environmental factors and genetic factors. The genetic changes that can lead to cancer may be inherited from parents, may also be caused by abnormal cell division or exposure to special environment after birth, and may also be carcinogenic environmental exposure, including some special substances, such as harmful chemicals and rays formed by tobacco burning.

　　At present, malignant tumor accounts for the first cause of death among urban residents in China. From 2000 to 2014, the onset age of cancer in China is moving forward every year, with an overall advance of about two years. Through the cooperation of surgery, internal medicine, radiotherapy and other multidisciplinary departments for many years, human beings have mastered the tools for early detection of cancer such as CT, ultrasound, tumor markers, and at the same time have many effective cancer treatment methods such as surgery, chemotherapy and radiotherapy.

　　Can cancer be prevented?

　　In fact, the formation of cancer is very slow, and it takes about 20 to 30 years for the human body to develop into cancer after long-term exposure to carcinogenic environment.

　　During this period, we have to go through many steps, such as cell transformation, precancerous lesions, carcinoma in situ, and gaining the ability of invasion and metastasis. In the previous twenty or thirty years, we had plenty of time to find and eliminate cancer. Therefore, early screening and diagnosis of cancer is particularly important.

　　"Gene mutation" and "immune escape" are two key factors in the formation of cancer. Gene mutation is a "restless" cell, and it will not stop when it stops proliferation. Immune escape is a "restless" cell that escapes the surveillance and attack of the immune system through various methods.

　　Can cancer be prevented? The answer is that some cancers are completely preventable.

　　In 2011, the World Health Organization proposed that one-third of cancers could be completely prevented; One third of cancers can be cured by early detection; One-third of cancers can use existing medical measures to prolong life, relieve pain and improve quality of life. This ratio means that, optimistically, cancer can not be fatal, pessimistically, some tumors can not be predicted and escaped.

　　Tumor prevention, the ideal state is to find and intervene in the precancerous lesions, so as not to let the precancerous lesions develop into cancer, such as lung cancer, which we are familiar with. If we intervene in time in the early stage of disease development, more than 90% can be cured.

　　The focus of cancer prevention is "etiological prevention"

　　The prevention of cancer is divided into three levels. For most of us, the emphasis should be on the primary prevention, that is, the "etiological prevention" of cancer, which is what we usually call "prevention of disease". Why pay attention to this level of prevention? Because of its long time, many opportunities, good effect and low cost.

　　Cancer prevention should "do something". Starting with improving the internal environment of our bodies, that is, enhancing our "immunity". Vaccination can improve the body’s immunity to specific viruses. Although there is no such thing as cancer virus, some viruses can indeed cause cancer. For example, HPV vaccine can prevent cervical cancer and hepatitis B vaccine can reduce the incidence of liver cancer.

　　In addition, you can keep your immune system in good condition by controlling your weight, exercising moderately and keeping your mood comfortable.

　　To prevent cancer, we must "do something." To do something wrong is to avoid carcinogenic factors in life. This includes external factors such as physics, chemistry and biology, as well as some internal genetic factors. According to the list of carcinogens published by the World Health Organization, a total of 116 substances are classified as a class of carcinogens, which are certain to cause cancer, including tobacco, alcohol, formaldehyde and so on. Reducing exposure to carcinogenic factors in daily life is an important step in cancer prevention.

　　The public’s awareness of smog prevention has weakened.

　　Paranoid, introverted, unwilling to communicate with friends, once family, emotion, work and other things go wrong, the psychological pollution index is higher, which belongs to the "cancer personality" that is often said.

　　Professor Zhi Xiuyi, director of the Propaganda Department of Popular Science of China Anti-Cancer Association and chief expert of thoracic surgery in xuanwu hospital, Beijing, said: "Nearly half of the lung cancer patients admitted in clinic are related to long-term depression, depression and emotional shock."

　　Mental factors can not directly cause cancer, but they often affect and reduce the immunity of the body with a chronic and persistent stimulus. It causes the imbalance of autonomic nervous function and endocrine function, makes cancer cells break through the defense of the body’s immune system, and then forms cancer.

　　According to the report of the World Health Organization, healthy exercise, diet and sleep can prevent 30%~50% of cancer, and many deaths caused by cancer can be avoided.

　　Feng Li, director of Chinese Medicine Department of Cancer Hospital of China Academy of Medical Sciences, said that staying up late and getting angry are a risk factor for cancer, but they are not the main key factors. Because the key factor of tumor occurrence is mainly internal factors.

　　In addition to keeping your mouth shut and keeping your legs open, you should pay attention to eating more grains, vegetables, fruits and beans to prevent cancer; Eat less red meat and processed meat; Eat less salt; Drink less alcohol; Do not smoke; Stay up late less.

　　In addition, "anti-cancer screening" can make "early cancer" strangle in the cradle ",and women ≥ Cervical cancer screening should be done at the age of 20, and it is best for women over 40 to do breast cancer screening, including breast ultrasound and mammography. Professor Zhi Xiuyi reminded that people over 40 years old had better do screening for esophageal and gastrointestinal tumors, mainly painless gastrointestinal endoscopy. When you are over 50 years old, do colorectal cancer screening, including fecal occult blood test and colonoscopy. Over 50 years old and smoking ≥ 20 packs/year, low-dose spiral CT is recommended. (High-risk groups can advance their age to 40)

　　In recent two years, people’s awareness of smog prevention has gradually weakened, and the number of people wearing masks on the streets in foggy days has decreased significantly. Many people seem to be used to it, and it doesn’t matter to run on the streets in foggy days.

　　Professor Zhi Xiuyi appealed to the public to pay attention to the health effects of inhalable particulate matter PM2.5 and smog weather. Minimize going out in foggy weather; If you have to go out, you should also try to reduce your stay outside, wear a protective mask when you go out, and reduce the intake of PM2.5

　

　

　　　　Official website in most colleges and universities seems to be a copy of the government’s official website template: the news and photos of school leaders attending activities, the used campus scenery … the serious and rigid style is not commensurate with the traditional lively and free college style. Just because of this, campus official website often appears very deserted. This is also the reason why official website was crowded with beautiful women. People need this lively and refreshing feeling too much.

　　　　So, what’s the intention of basking in the "Goddess of National People’s Congress" in official website on campus? Is to break the rules of silence? Many people don’t think that this move is just as pure as opening a fresh atmosphere. It is the enrollment season of colleges and universities, and it is associated with the background of colleges and universities grabbing students. Many people speculate that "girl students of the National People’s Congress" is actually an enrollment platform for the National People’s Congress as a public relations weapon to snatch students.

　　　　If this is the purpose, then playing the "beauty card" is too crude. The gathering of beautiful women on campus is pleasing to the eye, but studying is the main purpose, and finding emotional support is just a "sideline". This crudeness is precisely the silhouette of the lost spirit of the university-if a university comes to a situation where it attracts students by beautiful women rather than famous teachers, then the teaching style is too superficial.

　　　　Although beautiful teachers and sisters are pleasing to the eye, the talents of famous teachers and scholars can benefit people endlessly. The beautiful teacher elder sister won’t wait for you. After graduation, she will go into the society. What she will do is make love and mate with people. Only a free and strong academic atmosphere, only a famous teacher is knowledgeable, is an evergreen tree that permanently displays the charm of colleges and universities. The school shows its charm on the campus website, besides basking in some beautiful women, it should also bask in some famous teachers and masterpieces. Today’s university websites seem to have little space for famous teachers to show. The heavy treasures of the town and school will not be basked in, but some superficial beauty will be basked in, which is destined to become a short-lived carnival.

　　　　Xiaobian has something to say:Perhaps, the National People’s Congress basks in the "goddess" and just wants to make official website, which is serious and rigid, more relaxed and lively, with no other intention. However, since the "Goddess of the National People’s Congress" has caused widespread spit and noise, as a person who has experienced it, he can’t help but think of a little advice for his schoolmates: no matter how beautiful the goddess is, she will always be a schoolmate. "Goddess" basks on the school net, which can be seen, not met, and even more elusive. It’s better to retreat and form a net than to fish in the forest. The diaosi people attack the spring, and they still have to struggle and create on their own after all. Official website, the National People’s Congress, basked in the "goddess", perhaps just to create a relaxing moment. However, behind the spit and noise, there are also heavy worries: besides these superficial things, are there no other charms to show in colleges and universities that bask in beautiful scenery? Perhaps, the academic charm is gone, and we have to rely on the mentality of public entertainment to express our sense of existence.

　　Hypertension, depression, insomnia … … Even cancer, if someone tells you that there is a "hydrogen inhalation" therapy that can treat these symptoms, do you believe it? Hydrogen is a flammable gas. Does it really have such a "magical" effect when inhaled into the human body? What is the scientific principle behind it? Is it really effective or a psychological effect to treat diseases by absorbing hydrogen?

　　The reporter recently learned in an interview that this kind of "hydrogen therapy" is gradually being valued by the medical community, and the selective antioxidant properties of hydrogen are the key to the so-called "cure all diseases".

　　Why do people get sick?

　　The main reason is the imbalance of oxidation and reduction in the body.

　　To understand why hydrogen can cure diseases, we must start with why people get sick.

　　We should know that the human body is always in a dynamic balance with the surrounding environment. Under the action of pathogenic factors, such as bacteria and radiation, the original balance is broken, and the body is damaged, resulting in pathological changes in the function, metabolism and mental structure of tissues and organs, resulting in clinical symptoms and signs.

　　When human cells are oxidized, they will form oxidative damage. Medically speaking, it is because of internal and external factors that a large number of free radicals in the body erupt, which is called oxidative stress.

　　Free radicals are atoms, groups or molecules containing unpaired electrons. Free radicals themselves are essential substances to maintain normal life. Free radical reaction is the basis of energy metabolism. When people inhale oxygen and eat food, energy substances and substances that promote energy conversion undergo oxidation reaction in the body, thus producing a large number of free radicals. Free radicals in the human body are constantly produced, and will be continuously removed and maintained at a normal physiological level. Once there are too many or too few free radicals, it will cause adverse effects and even harm to the body.

　　When the oxidation degree of cells exceeds the antioxidant capacity of cells to remove oxides, it will form an imbalance between oxidation system and antioxidant system, that is, redox imbalance. Excessive free radicals, especially toxic reactive oxygen species, will begin to attack biological macromolecules and cause tissue and cell damage. Therefore, oxidative damage is the root cause of various diseases and body aging. Taking the treatment of human inflammation as an example, it is generally believed that scavenging oxygen free radicals is the most fundamental way to alleviate inflammatory reaction.

　　Principle of treatment:

　　Hydrogen can scavenge human toxic free radicals.

　　Xu Kecheng, a domestic oncologist and honorary president of Fu Da Cancer Hospital affiliated to Jinan University, told the Yangcheng Evening News reporter that "hydrogen therapy" is a new therapy that is gradually being valued by the medical community. The medical community has carried out more and more research on how many diseases, to what extent, and whether there are side effects.

　　Xu Kecheng introduced that no matter what kind of diseases people suffer from, there is a common factor, that is, the emergence of toxic free radicals in the body. Free radicals (reactive oxygen species) are divided into good and bad ones. Japanese scientists have found that hydrogen can specifically remove bad free radicals. Because one of the most typical and important chemical properties of hydrogen is its reducibility, which can selectively neutralize toxic free radicals. From the analysis of disease mechanism, oxidative damage is the most basic pathophysiological process of almost all diseases. Therefore, since hydrogen is a selective antioxidant, it is likely to have a therapeutic effect on most human diseases.

　　Why does hydrogen have selective antioxidant properties? It turns out that the reducibility of hydrogen is very weak compared with various reductants in the process of cell metabolism. According to the law of redox priority: for the same oxidant, when there are multiple reductants, it usually reacts with the reductants with the strongest reductants first. Therefore, in the normal process of cell metabolism, hydrogen basically has no effect. However, if it is in abnormal cells, the situation is different. For example, in tumor tissue cells, because a large number of free radicals are produced, the normal metabolic reaction cannot be carried out, so other reducing substances are insufficient, which gives hydrogen a chance to react chemically with free radicals, and the result is to cancel out unpaired electrons in free radicals — — Most unpaired electrons of free radicals come from oxygen atoms — — They can react with hydrogen to produce water, a stable substance, and free radicals that lose oxygen atoms become stable substances in this process.

　　Small side effects,

　　Because hydrogen itself is inactive

　　In Xu Kecheng’s Guan ‘ai Health Studio in Guangdong Province, the reporter saw that the seats next to the 15 "hydrogen-absorbing machines" set here were all filled with people who "sucked hydrogen" with trachea in their noses. The staff told the reporter that this machine can electrolyze water into a mixed gas with 66% hydrogen and 33% oxygen only by adding pure water or distilled water. The patient only needs to take a deep breath and inhale the gas into the body to complete a course of treatment. The time for each "hydrogen inhalation" course is at least one and a half hours. A 62-year-old Chen Yi told the reporter that she was diagnosed with gastric cancer several years ago. After a series of radiotherapy and chemotherapy treatments, the whole person became extremely weak. After starting to suck hydrogen in early August this year, she found that her physical condition had improved significantly. "After the first hydrogen inhalation, it was a sweat when I got home; After insisting on smoking for three times, I found that the sleep that I woke up once an hour has improved. Originally, Qing Wu’s face has also improved, and his physical strength has gradually recovered. Now he can go for a walk in the community every day. " Another Abreu also told reporters that he had liver cancer four years ago, and later had an operation to remove it. I didn’t expect it to recur last year. After being recommended to absorb hydrogen, the most obvious change is that sleep is better and the spirit is much better.

　　It turns out that in terms of anti-tumor, tumor cell walls produce more reactive oxygen species than normal cells, which affects cell proliferation, DNA synthesis and angiogenesis, and oxygen free radicals, as "second messengers", play an important role in intracellular signal transduction and can induce and maintain the carcinogenicity of cancer cells. At this time, as an antioxidant, hydrogen has the potential to treat tumor diseases. Moreover, scientists have found that compared with other antioxidant substances, hydrogen can easily pass through the cell membrane and organelle membrane, reach the required parts for reduction reaction, and selectively remove oxygen free radicals. At the same time, because hydrogen itself is inactive, it will not cause physiological function damage and metabolic disorder.

　　Progress is rapid,

　　But the biological safety needs to be verified.

　　The effect of hydrogen on human health can be traced back to 1975. At that time, someone published a paper in Science magazine, saying that continuous breathing of 8 atmospheres of 97.5% hydrogen for 14 days, high-pressure hydrogen can effectively treat animal skin malignant tumors, and that this is the effect obtained through anti-oxidation.

　　In addition, in 2001, French diving doctors also proved that breathing 8 atmospheres of high-pressure hydrogen can also treat the inflammatory reaction caused by Schistosoma hepatica infection, which proved for the first time that hydrogen has anti-inflammatory effect, and proposed that the direct reaction between hydrogen and hydroxyl radicals is the basis for treating inflammatory injury.

　　However, the above research has not attracted widespread attention, mainly because high-pressure hydrogen is difficult to be used as a general clinical treatment.

　　It was not until 2007 that Professor Naruto Ota of Japan Medical University succeeded in the experiment of treating animal cerebral ischemia with 2% hydrogen, and it was published in the journal Nature Medicine, and "hydrogen therapy" finally attracted the attention of the whole world. 2007 is therefore recognized as the first year of "hydrogen medicine".

　　Since then, the research of hydrogen biology has begun to rise. The United States, Japan and China are the countries that have studied the medical biological effects of hydrogen the most, and each country has dozens of research institutions to participate.

　　In China, Sun Xuejun, a professor at Shanghai Second Military Medical University, is considered to be the first person to introduce hydrogen therapy, also known as "the first person in hydrogen medicine in China". Professor Sun Xuejun said that he has been engaged in gas effect research for a long time, but he didn’t start to study the medical effect of hydrogen until he saw the research results of Akio Ota in 2007, and gradually found that this therapy was really useful.

　　Nowadays, the research results of hydrogen biology in domestic medical circles are increasing. Take the number of topics related to "hydrogen medicine" included in China HowNet as an example. In 2007, the topics related to "hydrogen" were all related to energy. After 2007, a large number of papers on "hydrogen" and the medical effects of various diseases appeared, involving mental illness, heart disease, cancer and other fields. Some academicians also began to study "hydrogen medicine". Among them, Wang Hongyang, academician of China Academy of Engineering and director of National Hepatocellular Cancer Science Center, also led the research group to complete the Study of Hydrogen Therapy for Liver Injury, which was published in the internationally renowned Journal of Hepatology.

　　In 2014, Zhong Nanshan, an academician of China Academy of Engineering, discovered that hydrogen is effective for chronic obstructive pulmonary disease. In his speech at the World Thoracic Congress, he pointed out that "hydrogen molecules are mainly aimed at chronic diseases, and the most basic thing is the enhancement of antioxidant stress, not the simple repair, which is conducive to the recovery of the body. The concept is to treat the cause rather than the symptoms."

　　In March, 2014, the professional committee of hydrogen molecular biomedicine of China Medical Care International Exchange Promotion Association was also announced.

　　However, at present, "hydrogen medicine" is still in the basic and clinical research stage. Xu Kecheng told reporters that he hopes to collect as many clinical cases as possible through public welfare studios. Because some experts pointed out that although hydrogen has been found to be effective for many diseases, the biological mechanism of this effect still needs further study, and its clinical effect needs to be supported by sufficient evidence. For example, Dong Wenbin and Zheng Gaoli from the Institute of Pharmacology of Zhejiang Academy of Medical Sciences once wrote that the biological safety of hydrogen can not be fully proved at present, and many problems about hydrogen treatment need further study.

　　Key reminder:

　　Self-hydrogen therapy is not recommended.

　　At this point in the article, it is particularly worth reminding that the use of hydrogen to treat diseases should still be operated under the guidance of professional doctors, and it should never be used casually.

　　For example, the hydrogen used in hydrogen balloons is not recommended for treating diseases. In this regard, Lin Xinyong, president of Shanghai Shumei Medical Technology Co., Ltd. said that the gas normally inhaled by the human body must pass the safety tests such as toxicology and biocompatibility before it can be used. Even though water electrolysis can produce hydrogen, there are risks if the related equipment parts are non-medical grade.

　　Wei Youzhen, a professor at the Oriental Hospital affiliated to Tongji University, also said that the hydrogen used in hydrogen balloons is usually industrial hydrogen, and its source is not necessarily generated by water electrolysis. There may be other gases doped, so the purity is not enough, so it is not suitable for human inhalation, and it is not conducive to treating diseases.

　　CCTV News:The 26th is the National Heart Failure Day. Since 2015, relevant departments have determined this day, and this year is the third. As one of the most important and serious cardiovascular diseases, heart failure is a serious problem faced by aging countries all over the world, but it is often ignored by patients.

　　What is heart failure? Look at these "sad" symptoms. Have you won?

　　When the heart load increases or the muscle is damaged, its blood pumping function decreases, just like a "ball" with decreased elasticity. The output blood volume can’t meet the needs of organs and tissues, and the blood can’t flow back to the heart smoothly. This state is called heart failure, which is referred to as "heart failure" for short. The following symptoms are common: shortness of breath when lying down, heavy chest like a heavy stone, sudden tightening of clothes and shoes, loss of appetite, dizziness, anxiety, persistent cough, fatigue or fatigue all day, oliguria and edema of lower limbs. Experts suggest that the above-mentioned "sad" symptoms should be treated promptly. Exclude related diseases, and treat them in strict accordance with the doctor’s advice after diagnosis, and do not change or stop using drugs by yourself.

　　Half of the neglected severe cases died within five years after diagnosis.

　　At present, the incidence of heart failure is rising rapidly and becoming younger. It is estimated that there are more than 11 million patients with heart failure in China, and one in every 10 people over 70 years old suffers from heart failure. There are also some young patients aged 30 and 40 in clinic.

　　In addition, there are many "reserve forces" of heart failure in China-coronary heart disease, hypertension, valvular heart disease, diabetes and other diseases can all cause heart failure in the later stage.

　　The mortality rate of heart failure is very high, about 50% patients died within 5 years after diagnosis, and about 20% patients died within 1 year after diagnosis. The mortality rate is even 2-3 times that of cancers such as breast cancer and intestinal cancer.

　　Although there are many patients with heart failure in China, many people don’t understand it. About one-third of them mistake the symptoms of heart failure for the normal phenomenon of aging, and one-quarter of them go to the hospital at least one week after the symptoms of heart failure appear.

　　Actively prevent and control early diagnosis and early treatment. Remember these can save lives!

　　The key to the prevention of heart failure is to intervene the risk factors of heart failure. If you want to have a good prognosis, the key point is to intervene early, and first actively control various cardiovascular risk factors, such as obese patients to lose weight.

　　Those without related diseases should stay away from unhealthy lifestyles, ensure adequate sleep and avoid fatigue. Emotional excitement is a major factor in inducing heart failure, so you should keep a cheerful mood at ordinary times and keep a good attitude when something happens. Recently, the temperature has plummeted, and the cold weather is the "enemy" of heart patients, which is easy to cause the condition to deteriorate, so we should pay attention to keeping warm and keeping out the cold.

　　Many patients don’t understand the characteristics of heart failure, stop taking drugs on their own when their symptoms improve slightly, and don’t have reasonable life management, which leads to repeated attacks, hospitalization, aggravation and even death, which brings great burden to society and families. According to statistics, patients with heart failure are hospitalized for an average of 2.4 times a year, and the average length of hospitalization is as long as 22 days. The annual hospitalization fee is nearly 40,000 yuan, but the medicine fee only accounts for 8%. Experts pointed out that if patients can regulate effective medication, the chances of hospitalization can be reduced.

　　In recent 20 years, the emergence of some innovative drugs has greatly improved the prognosis and mortality of patients with heart failure, but the cost is high, and experts also call for it to be included in medical insurance as soon as possible.

　　"Without the health of the whole people, there will be no overall well-off." Medical and health services are directly related to people’s health. With China paying more attention to prevention and health promotion, shifting the focus of work and sinking resources, the development mode has changed from disease-centered to health-centered; It is believed that with some old-age care institutions and family wards improving their mechanisms, allowing patients to go to hospitals to mainly adjust their medication and implement it in family wards, and all sectors of society will increase the prevention of related diseases by popular science, which will surely significantly improve people’s health level and promote the construction of a healthy China.

In the early morning of March 24th, after Tanas, a member of top combine, sent a lawyer’s letter saying that his ex-girlfriend Chen Mumu had made a rumor, Chen Mumu also sent Weibo to respond to this matter for the first time. His tone was tough and domineering, indicating that he had no intention to enter the entertainment circle, and he would not say that it was understandable to send a letter for the sake of heat, but everything would be properly handled and faded. As long as the parties still had some conscience in their hearts, they would not send this letter. It seems that Chen Mumu didn’t seem to take this lawyer’s letter from Xiao Wufa to heart.

　It is reported that on March 23rd, Chen Mumu, who reported that Lemon was a "mistress", posted a message again, revealing a chat record with Tanas’s agent. The remark was that Miss Ye, the agent of Xiaowu, apologized on behalf of Tanas, but for the sake of the company’s position, she would not apologize publicly, and also revealed that "the company was in a state of semi-abandonment for Xiaowu" and prayed for forgiveness to solve the matter privately. After Chen Mumu disclosed the agent’s chat record, Tanas Studio published a lawyer’s letter directly through the company, pointing out that what Chen Mumu said was not true at all and was suspected of malicious forgery, and requested to stop the infringement, delete false and malicious information, and not mislead, follow comments or spread. Tanas himself and Lemon also forwarded Weibo’s statement: "People are desperate and helpless."

After Chen Mumu disclosed the agent’s chat record, Tanas Studio published a lawyer’s letter directly through the company, pointing out that what Chen Mumu said was not true at all and was suspected of malicious forgery, and requested to stop the infringement, delete false and malicious information, and not mislead, follow comments or spread.

In the early morning of March 24th, after Tanas sent a lawyer’s letter, Chen Mumu responded domineering and was not afraid of the lawyer’s letter.

Previously, on March 19th, Xiaowu Tanas and Lemon announced their love affair. In the early morning of March 20th, netizen Chen Mumu revealed that she and Xiaowu had a relationship before. They broke up on September 3rd last year and originally planned to celebrate Xiaowu’s birthday in Maldives on September 17th, but Xiaowu suddenly changed her mind and said that she wanted to be alone. After sorting out the timeline, she speculated that she was actually with Lemon at that time. Before the two broke up, Xiaowu played games with other girls, and later used a couple nickname. Finally, she said, "Now I understand who it is."

After netizens "eat melons", they all said, "So Lemon is" used to three "?" "Small three with small five is really a perfect match! Groups of three or five are not just talk. "

This is not the first time that Lemon has been called a mistress.

Previously, Lemon had intervened in the marriage of Liu Yuxin and Li Meng, when Liu Yuxin was still nursing. At first, Lemon denied it and used many means to defend himself.

Finally, under the pressure of public opinion, I admitted the fact of my third party, and I also admitted my plastic surgery.

After the love affair with Tanas was exposed, Lemon was also introduced into the relationship between Tanas and Wu Youxuan. Some netizens found that the back photo of Xiaowu Tanas and the picture of Lemon walking the dog were taken in the same place, and they also had the same fisherman’s hat, canvas shoes and cowboy suit.

Coincidentally, in the video shared by Lemon earlier, netizens also found Jin Shengen’s photo frame.

After the two were exposed to love, some netizens claimed to be friends of Xiaowu’s wife, and broke the news that Xiaowu had already married his girlfriend Wu Youxuan and bought a house in Zhuhai. During the enlistment of Xiao Wu, his girlfriend took a long bus to visit him in Korea every month, and they were also pulled out of the same pet photo of Weibo.

On March 19th, Tanas, the "Little Five" of Everyday Upward, officially announced her love affair with Lemon: "I want to walk with you in sunny days and hold an umbrella for you in rainy days", and responded to the online news that she did have a relationship with Ms. Wu, but she had already separated peacefully. "Love is a private matter and has the right to choose not to make it public." Lemon then forwarded a sweet response: You are my man and my little prince, and finally I can’t unscrew the bottle cap.

While Tanas officially announced her love affair with Lemon, she also admitted that she had a relationship with Wu Youxuan, saying that they broke up peacefully, and seemed to deny the rumor that she was cheating on her and that Lemon was a mistress again.

Later, in the sun, a long picture and a screenshot of a chat appeared, which was suspected to imply that Lemon was "stupid and an idiot" and revealed that Tanas had divorced.

Yu is talking about an actress "Molly" whom he is familiar with in a long article, which is suspected to imply Lemon who just announced her love affair with Tanas. He said that the article "Jasmine" is written by an actress who is familiar in the entertainment circle. Her behavior is perverse and her personality is outstanding. She is a typical material for a good person whose personality determines her fate. In the article, he tries his best to be objective, without boasting or venting his anger. He simply records her words and deeds, as well as her views and comments. And Yu Zheng told the actress that she would write this article, but didn’t show it to her, saying, "I hope to see myself in other people’s eyes and enlighten her!" "

In a long article, he revealed that he had asked Jasmine for the hot search of "Little Three" after years of no contact. As always, the other party frankly admitted it, but said that he didn’t know before the contact. The night before yesterday, she suddenly contacted herself and asked what she thought of her unexpected hot search. Then she told her boyfriend that she was going to be exposed. The reason was that her boyfriend had divorced when he met her and didn’t want to be called mistress again. Yu Zheng advised her to be silent at this time, but she refused to listen, saying, "So I don’t think people’s nature can be changed. It’s really stupid and idiotic."

On the afternoon of March 19th, Wu Youxuan issued a statement, which stated: "Wu Youxuan has broken up with Tanas, and everything involving Tanas and Lemon has nothing to do with Wu Youxuan." Later, Wu Youxuan forwarded the statement and sent a message: "Thank you for your concern for me. During the epidemic, I hope that all my friends will protect themselves and their families, wish you and your families good health and pray for the early end of the epidemic."

The manuscript is synthesized from Sina Weibo and Sohu Entertainment.

Special feature of 1905 film network Caring for nurses and protecting people’s health. May 12th is the 111th International Nurses’ Day. Yamei, an actress who plays a nurse in the film "Today’s Film Review", came to know the sacred profession of nurses with us.

Nowadays, epidemic prevention work is normalized, and nucleic acid testing is also carried out frequently. When testing nucleic acid, nurses wearing protective clothing are very hard. The theme of this year’s International Nurses’ Day, "Caring for Nurses and Protecting People’s Health", is also concerned about this angle.

The host said: "Whether from the perspective of nursing or protection, it seems that the responsibility of this word’ protection’ is even heavier." Yamei recalled the role of a nurse in the film. She added: "When testing nucleic acid or putting on protective clothing, they show care and patience. It takes more than ten steps to put on protective clothing, but in these processes, your negligence in one step may cause infection."

By playing the role of nurse, Yamei realized the hard work of nurses. Among them, putting on and taking off protective clothing is a very complicated process, not simply wearing it layer by layer, and there are many details to pay attention to.

Yamei said: "The first step is to wash your hands first, then wear the first layer of headgear, then wear the first layer of protective mask, then wear the first layer of shoe cover, because it is two layers, and the third layer of protection is a comprehensive package, then the second layer of headgear, and finally wear isolation gown, and then wear goggles. Before wearing goggles, there is a detail, that is, you must clean the goggles with anti-fog agent, because you are long. When I first finished wearing protective clothing, I was already sweating before I entered the real work area. "

The medical care we often talk about actually refers to two groups: doctors and nurses. Doctors are responsible for making diagnosis and making treatment plans, while nurses are responsible for carrying out doctors’ orders, nursing patients and giving medicines to different patients.

As the so-called "three-point treatment and seven-point care" means, friends who have been hospitalized will feel that nurses are the ones who have the most contact. Most of the time, nurses are doing meticulous nursing work. In addition, nurses also play the role of psychological counseling. They usually show patients a warm and positive side, so that patients can have a more positive attitude towards the disease, which is very important for the recovery of health.

Before shooting Chinese Doctors, Yamei also went through closed training in order to better integrate into the role, among which the intravenous blood sampling class left the deepest impression on her, because she was very afraid of needles. Yamei said, "When the consultant took the blood needle out in front of me, I cried at once."

She has been looking for ways to overcome it, and then she thinks that under the epidemic situation, every nurse has her own fears, but they can all overcome these fears and face difficulties bravely. She also secretly made up her mind that if she really wants to play the role of a good nurse, she must overcome her fear of needles.

More understanding, more understanding. Yamei said: "In fact, I will understand the work of medical staff better after filming that play." Some patients are very anxious when they go to see a doctor, and they think why doctors or nurses ignore themselves. In fact, they all have a reason. In the movie Chinese Doctors, the director Wen said, "These people came to the queue last night. Which one do you think I will take for your wife?" All these experiences make Yamei feel that we should have a better understanding of angels in white.

Under the epidemic, we witnessed the courage of nurses and their love. Not long ago, there were two nurses in the Sichuan aid medical team. After they successfully completed their work, Kang Xin, a male nurse, proposed marriage. The program also invited Kang Xin to share his marriage proposal with everyone.

Kang Xin: We received an order on the 30th to set up a medical team in Sichuan Province. My girlfriend and I signed up at the same time and were selected as a member of the medical team to aid Kyrgyzstan. Before going, we discussed that if we could come back safely, we would get a marriage certificate together. On the 27th, our task was basically completed, and we were going back to Sichuan on the 28th, so I discussed it with my friends and proposed to her on the evening of the 27th. We folded a rose with a napkin, a balloon, and a small ring made of a mask. The mask has a plastic strip. I made a ring shape with the plastic strip, and then wrapped it with the lace of the mask to make two shapes like rabbit ears.

Whether female nurses or male nurses, they should have a gentle and delicate side to show consideration to patients, and at the same time, they should have a brave and enthusiastic side to give patients the courage and hope to overcome the disease. There are also many images of nurses in our movies, such as movies and Chinese Doctors. The challenges faced by nurses are different in different periods, but there is an unchanging spiritual core, that is, the dedication of putting patients in the first place forever and saving lives.

Medical staff are great ordinary people. They cast the last wall to block the epidemic and the people with their own flesh and blood. They have no hesitation and great love. Just like this year’s theme, "Care for the nurses and protect the people’s health", I hope that while they protect the people’s health, the whole society will also care more for the nurses.

Wang Jianlin introduced SKP Department Store, which is known as "the best shopping mall in China", to cooperate with wanda plaza, Chuhehan Street, Wuhan, Hubei.

On June 3, The Paper (www.thepaper.cn) inquired about the industrial and commercial information and saw that Beijing Hualian (SKP) Department Store Co., Ltd. took over the asset management business of the second block of Chuhehan Street (Wanda J3 plot) and the wanda plaza of Chuhehan Street in Wuhan Central Cultural District in the form of equity acquisition.

According to The Paper, the business that SKP took over this time does not include Wuhan Hanxiu Theater.

According to the data, Beijing Wanda Lianda Commercial Development Co., Ltd. was incorporated on April 12, 2021 with a registered capital of 10 million yuan. At present, Beijing Hualian Hanjie Commercial Management Co., Ltd. holds 60% of the shares, and Dalian Wanda Commercial Management Co., Ltd. holds 40% of the shares. Beijing Hualian Hanjie Commercial Management Co., Ltd. is 100% owned by Beijing Hualian (SKP) Department Store Co., Ltd.

Some analysts said that for SKP and Wanda, SKP has always wanted to land in Central China, and Wanda also wants to introduce high-end businesses to boost the consumption quality of Hanjie.

In fact, as early as the end of 2020, it was reported that SKP would acquire Wuhan Wanda Han Street Project.

On May 24th, SKP, a high-end department store under Beijing Hualian Group, signed a contract to settle in Wuchang District at the signing meeting of the second quarter investment promotion project in Wuhan. This is the third project that SKP signed after Hohhot and Hangzhou this year, and the fourth SKP that was officially started after Beijing, Xi ‘an and Chengdu. Wanda plaza of Chuhe Han Street is expected to be retired at the end of August and handed over to Wuhan Hualian (SKP) Department Store for renovation. It is expected to open after 2023.

Beijing SKP is a joint-venture department store invested and built by Beijing Hualian Group, which is positioned as high-end luxury and fashion, and is one of the most iconic fashion luxury department stores in the world. In 2018, the annual sales of SKP in Beijing reached 13.5 billion yuan, setting a new record for the development history of department stores and shopping centers in China commercial market. In 2019, Beijing SKP achieved sales of 15.2 billion yuan in a single store, ranking first in the world in terms of sales output per square meter and second in the world in terms of sales output per single store. In 2020, Beijing SKP’s sales revenue was 17.5 billion yuan, an increase of 15.13% compared with 2019. Therefore, SKP is considered as the most profitable shopping mall in China.

As for why SKP chose to enter Wuhan in the form of cooperation with Hanjie Wanda, some insiders said that Chuhe Hanjie was large enough. In addition, Chuhe Hanjie Wanda was originally positioned as a high-end consumer group, so it was reserved for heavy luxury in the early stage of construction. After SKP took over, the hardware transformation conditions were not difficult.

According to the data, Wuhan Wanda Chuhe Hanjie Project is located in Wuhan Central Cultural Center. It is a world-class cultural tourism project built by Wanda, which takes culture as the core and integrates the functions of tourism, commerce, commerce and residence. This project is the largest investment in the cultural industry of a single project in China, with a pure cultural investment of 8 billion yuan, a total investment of about 30 billion yuan and a total construction area of 3.4 million square meters. It officially opened on September 30, 2011.

　　In recent years, Singapore Telecom’s fraud cases have been rampant, and fraud methods and routines have emerged one after another, which is hard to prevent. Recently, dozens of China citizens have been "recruited" in Singapore in just one month. The Embassy of China in Singapore recently issued a reminder, hoping that local China citizens will be highly guarded against telecom fraud.

　　Fraud cases increased by 40%

　　According to the latest data released by the Singapore police, in the first half of 2019, 10 types of fraud cases in Singapore surged by 40% to 3591 compared with the same period of last year; The amount of fraud soared from S $59.2 million to S $83.1 million (equivalent to about RMB 430 million). Among them, e-commerce, loans, sexual services and online love fraud are the majority, accounting for 80% of the total number of 10 types of fraud cases, 58% more than the same period last year. In an online love scam, the victim lost as much as S $2.42 million (equivalent to about RMB 12.5 million).

　　According to the information released by the China Embassy in Singapore, in the past month, the Embassy has received dozens of China citizens who have been defrauded by telecommunications, and the amount of help-seekers has reached several million yuan. Most of the deceived people are international students.

　　Fraud syndicates usually operate internationally, which makes it difficult for law enforcement agencies to ban fraud syndicates. The stolen money is transferred to foreign bank accounts through local money donkeys, which makes it more difficult for law enforcement authorities to trace it. In this regard, the Singapore Commercial Affairs Bureau established a transnational commercial crime task force in October 2017 to investigate transnational fraud cases. The working group has cooperated with Malaysian and Hong Kong police to launch six joint operations against cyber loverboy. In April this year, two Nigerian loverboy operating in Malaysia were arrested and sent to Singapore.

　　Pretend to be a law enforcement officer

　　China’s Embassy in Singapore again issued a consular reminder on 17th, hoping that local China citizens would take precautions against telecom fraud.

　　The Embassy quoted the Singapore Police Force as saying that the telecom fraud cases in Singapore are on the rise. In various names, such as the staff of the Embassy of China in Singapore, the police in China or Singapore, the officials of the new Ministry of Manpower or Immigration Bureau, and the staff of DHL Express Company or local telecom company, fraudsters lied that the receiver or his relatives were suspected of committing a crime, in an attempt to trick the victim into sending money to a designated account or obtaining his online banking login information and password.

　　It is reported that the Embassy of China in Singapore recently received a request for help from a citizen in New China, claiming that he had suffered telecom fraud and suffered heavy economic losses. The suspect claimed to be a staff member of DHL Express Company, and lied that the courier sent by the victim to China contained contraband and was detained by China Customs. Subsequently, the suspect transferred the call to Beijing’s "police officer" and "prosecutor", while the "police officer" and "prosecutor" lied that the victim was suspected of an international crime case (fraud, money laundering, etc.) and produced a forged "arrest warrant", demanding the victim to provide personal account information and dynamic passwords for online banking login and transfer, and stealing huge amounts of money from the account. In the meantime, the suspect also coerced the victim to download the so-called "public security internal security monitoring software" to block the victim’s cell phone signal.

　　, so that it can not receive the short message of account change notification sent by the bank in time, and miss the best alarm opportunity. The Embassy reminded that China citizens in Singapore should stick to the "Three Musts" and "Three Don ‘ts" if they receive strange phone calls. The "Three Essentials" are to verify with the China Embassy or the Singaporean police through credible channels, to dial back according to the calling number after 5 minutes, to communicate with family and friends, and to handle it calmly; "Three Don ‘ts" means don’t trust calls from unknown sources, don’t listen to fraudsters’ requests for money transfer, don’t disclose personal identity and bank account information, and don’t give fraudsters any opportunity.

　　If you are unfortunately cheated, you should immediately report to the Singapore police, and contact the bank where I opened the account, and take measures to freeze the account, recover the cheated funds or other stop-loss measures. When necessary, I should report to the public security organ of my domestic domicile. If I can’t report the case directly, I can report it through my relatives in China.

　　Set up an anti-fraud center

　　In order to combat and prevent fraud, the Singapore police and the Commercial Affairs Bureau have set up anti-fraud centers, which will help reduce the economic losses of the deceived.

　　The anti-fraud center was established on June 18th this year. The center cooperates with banks, telecommunications companies and e-commerce platforms to quickly freeze bank accounts involved in fraud, cut off telephone lines used by fraudsters and be alert to users’ suspicious accounts on payment platforms.

　　According to local media reports, since its establishment two months ago, Singapore Anti-Fraud Center has submitted about 1,000 police reports on e-commerce fraud and loan fraud, frozen 815 fraudulent bank accounts and recovered economic losses of $850,000.

　　Before the establishment of Singapore Anti-Fraud Center, it took 14 to 60 working days for banks to freeze suspicious accounts. In addition, when investigators want to ask for information from banks, they must submit various forms. At present, the time for banks to freeze suspicious accounts has been shortened to a few days, and the police only need to apply once to obtain all relevant information, which greatly improves the efficiency of investigating fraud cases. However, this also reflects that there is still much room for improvement in anti-fraud work of banks. With the increasingly rampant fraud, banks may have to re-examine and adjust the balance between customer privacy and anti-fraud.

　　In addition, telecommunications companies and e-commerce companies are also more active in cooperating with law enforcement agencies. Telecommunications companies cut off suspicious telephone lines within the same day as the police request; The e-commerce platform actively monitors and deletes false accounts to stop the occurrence of e-commerce fraud at the source. The digital platform Carousell launched machine learning technology in March, effectively preventing the creation of 75,000 new accounts. (Li Yazhou Jun, special correspondent of Legal Daily in Singapore)