Recently, the World Health Organization’s International Agency for Research on Cancer (IARC) released the latest global cancer burden data in 2020.

Data display:

In 2020, 19.3 million people will be newly diagnosed with cancer and nearly 10 million will die.

One in five people will get cancer in their lifetime;

One in every eight men and one in every eleven women will die of cancer;

Five years after cancer diagnosis, the number of survivors is about 50.6 million;

Breast cancer has become the most common cancer in the world;

It is estimated that by 2040, 28.4 million people around the world will be diagnosed with cancer.

In 2020, the incidence of female breast cancer surpassed that of lung cancer for the first time, becoming the most common cancer in the world. However, lung cancer is still the cancer with the largest number of deaths worldwide.

▲ In 2020, the types, number and proportion of major new cancers in the world (data from IARC official website)

▲ In 2020, the types, number and proportion of major cancer deaths in the world (data from IARC official website)

Lung cancer is still the largest cancer in China.

Global data:

More than 2.2 million people in the world have been newly diagnosed with lung cancer, accounting for 11.1% of the newly diagnosed cancer in the world, that is, one in every nine new cases is lung cancer.

In terms of gender, more than 1.43 million men and more than 770,000 women are newly diagnosed with lung cancer. The proportion of new cases of lung cancer in men and women is 14.3% and 8.4% respectively. Lung cancer ranks first among men and third among women.

▲ Global male cancer deaths in 2020 (data from IARC official website)

▲ The global number of female cancer deaths in 2020 (data from IARC official website)

Among the 10 million cancer deaths in the world, nearly 1.8 million are lung cancer, accounting for 18%, and almost one in every six cancer deaths is lung cancer.

In terms of gender, more than 1.18 million men and more than 600,000 women died of lung cancer, accounting for 21.5% and 13.7% of male and female lung cancer deaths respectively. Lung cancer ranks first among male cancer deaths and second among female cancer deaths.

China data:

In China, lung cancer is still the first cancer in terms of morbidity and mortality.

▲ Cancer incidence and deaths in China in 2020 (data from IARC official website)

▲ Incidence and death of male cancer in China in 2020 (data from IARC official website)

▲ Incidence and death of cancer among women in China in 2020 (data from IARC official website)

In 2020, there are more than 810,000 new cases of lung cancer in China, accounting for 17.9% of the newly diagnosed cancer cases in China, that is, one of less than six patients is lung cancer.

In terms of gender, nearly 540,000 men in China and more than 270,000 women in China were newly diagnosed with lung cancer, accounting for 21.8% and 13.2% of the cases of male and female cancers in China respectively. Lung cancer ranks first among men in China and second among women in China.

At the same time, more than 710,000 people died of lung cancer in China, accounting for 23.8% of the cancer deaths in China, and almost one in four cancer-related deaths is lung cancer.

In terms of gender, more than 470,000 men in China and 240,000 women in China died of lung cancer, accounting for 25.9% and 10.2% of the male and female cancer deaths in China, respectively, and lung cancer ranks first among the male and female cancer deaths in China.

Behind every number is the sad change of a person and a family. The best way to deal with lung cancer is still prevention and control, especially early screening for high-risk groups.

60% of the high-risk population of lung cancer in China did not undergo LDCT screening.

Practice has proved that low-dose spiral CT(LDCT) is 4-10 times more sensitive to detect early lung cancer than conventional X-ray chest film, and can detect early peripheral lung cancer.

According to the data of the International Action Plan for Early Lung Cancer, 85% of stage I peripheral lung cancer can be found in the annual screening of LDCT, and the expected survival rate of patients after 10 years is 92%. The national lung cancer screening test in the United States has proved that LDCT screening can reduce the mortality of lung cancer in high-risk groups by 20%.

However, a recent study published in the Journal of the American Medical Association showed that researchers from Henan Cancer Hospital and other institutions analyzed the data of urban cancer early diagnosis and treatment projects in Henan Province from 2013 to 2019 and found that the overall participation rate of LDCT was 40.16%, which means that nearly 60% of the high-risk population of lung cancer were not screened.

The American Cancer Society (ACS) recommends that people at high risk of lung cancer receive LDCT screening regularly every year.

The risk assessment factors of lung cancer screening proposed by national comprehensive cancer network (NCCN) guidelines include: smoking history (present and past), radon exposure history, occupational exposure history (arsenic, chromium, asbestos, nickel, cadmium, beryllium, silicon, diesel exhaust gas, soot and soot), malignant tumor history, family history of first-degree relatives with lung cancer, chronic obstructive emphysema or pulmonary fibrosis history, and passive smoking history.

According to the risk status of lung cancer, it can be divided into three groups: low risk, medium risk and high risk:

?　Low risk group: Age < 50 years and smoking history < 20 packs a year (600 cigarettes/year).

?　Medium-risk group: Age ≥50 years, smoking history or passive smoking contact history ≥20 years, no other risk factors.

?　High risk group：

① Age 55 ~ 74 years, smoking history ≥30 packs a year (600 cigarettes/year), quitting smoking history < 15 years;

② Age ≥50 years, smoking history ≥20 packs of years, and risk factors other than passive smoking.

Suggestions on the diagnosis and treatment standard of primary lung cancer (2018 edition) in China:

High-risk group ① people should participate in LDCT lung cancer screening;

If there is a high-risk factor of lung cancer in the high-risk group, LDCT lung cancer screening should also be carried out.

Screening frequency: It is recommended that the interval of screening is 1 year, and the screening mode with an interval of more than 2 years is not recommended. If the annual screening is normal, it is recommended to continue screening every 1 ~ 2 years.

Screening management: It is suggested that nodules with diameter ≥5 mm need further examination.

Note: LDCT screening is not recommended for people who cannot tolerate possible lung cancer resection or serious life-threatening diseases.

Early lung cancer: SBRT has the same effect as surgery.

With the wide application of LDCT screening in high-risk population, more and more early lung cancer can be detected. For operable early non-small cell lung cancer (NSCLC, accounting for about 85% of all lung cancers), the standard treatment mode is radical surgery; For patients who are inoperable or refuse surgery, local radiotherapy is the standard treatment mode.

Compared with conventional radiotherapy, SBRT significantly improves the local control rate and the survival rate of patients with early NSCLC. The local control rate of SBRT in the treatment of inoperable early NSCLC is over 90%, which is equivalent to surgery.

In 2012, NCCN guidelines recommended that SBRT become the first choice for inoperable early NSCLC. In 2018, the American Association of Clinical Oncology (ASCO) officially approved SBRT as the standard treatment for early inoperable NSCLC.

SBRT has become an important radical treatment for early NSCLC, especially for patients who are inoperable or refuse surgery.

Indications of SBRT

Early inoperable NSCLC: old age, serious medical diseases, T1 ~ 2n0m0 stage.

Early NSCLC that can be operated but refuses to operate.

For early clinical lung cancer that cannot be diagnosed pathologically or refuses to be diagnosed pathologically, SBRT treatment can be considered if the following conditions are met:

(1) The definite imaging diagnosis focus gradually increased during the long-term follow-up (> 2 years), or the density and proportion of ground glass shadow increased, or accompanied by malignant features such as vascular crossing and edge burr-like changes; At least two imaging examinations (such as chest enhancement+1 ~ 3 mm thin-slice CT and whole-body PET or CT) indicate malignancy;

(2) confirmed by MDT discussion of lung cancer;

(3) Patients and their families fully informed consent.

Relative indications:

(1)T3N0M0；

(2) Simultaneous multiple primary NSCLC.

References:

1.2020-12-16 e Medicine Global Authoritative Report: In 2020, there will be 19.3 million new cancers worldwide, and lung cancer is no longer the most common cancer! 》

2. China lung cancer diagnosis and treatment standard (2018 edition)

3.2020-11-04e Drug Global "Data of more than 50,000 people in China: Nearly 60% of the high-risk population of lung cancer did not participate in the screening. What factors are affecting it? 》

4. China Expert Consensus on Stereotactic Radiotherapy for Early Non-small Cell Lung Cancer (2019 Edition)

　　Cctv news(News Network): The Ministry of Agriculture and Rural Affairs announced today (October 29) that since the beginning of this year, China’s agricultural and rural economy has maintained a good momentum of development in general, achieving stability and progress.

　　Grain production is improving steadily, with a bumper harvest of early rice in summer and another bumper harvest in autumn.

　　The supply of "vegetable basket" products is of high quality. The production capacity of live pigs is at a reasonable level, and the market supply is guaranteed in the later period.

　　The results of poverty alleviation continued to be consolidated. 832 poverty-stricken counties have cultivated two or three leading industries. At the end of September, the number of migrant workers out of poverty reached 32.687 million, exceeding the annual target.

　　The industry of enriching the people in rural areas has been cultivated and expanded. In the first three quarters, the added value of agricultural and sideline food processing industry increased by 1.9% year-on-year, and the online retail sales of agricultural products reached 374.51 billion yuan, up by 8.8% year-on-year.

　　Driven by industry and employment and entrepreneurship, farmers’ income has grown steadily. In the first three quarters, the per capita disposable income of rural residents was 14,600 yuan, a real increase of 4.3%.

　　The recent exposure of "Hainan Boao Yinfeng Kangyang International Hospital involved in the vaccination of fake nine-valent HPV vaccine" has poured a pot of cold water on the vaccination boom of HPV (human papillomavirus) vaccine.

　　Over the past few years, in the upsurge of public opinion, the nine-valent HPV vaccine has gradually become a vaccine "online celebrity". An endless stream of cross-border vaccinators even once "stopped supplying" the nine-valent HPV vaccine in Hong Kong.

　　On April 28th, 2018, under the great expectation, the nine-valent HPV vaccine was officially approved for listing in Chinese mainland at the speed of rocket.

　　Before listing, the huge demand crowd gave birth to chaotic outbound vaccination intermediaries, and illegal smuggling was also common. This industrial chain is still active today.

　　The "fake nine-valent HPV vaccine" incident uncovered the gray side of the HPV vaccine business.

　　According to the notification of Hainan Provincial Health and Health Commission on April 28th, Hainan Boao Yinfeng Kangyang International Hospital (hereinafter referred to as "Yinfeng Hospital") was suspected of illegally vaccinating 38 people with HPV vaccine in January 2018. The "victim" of the incident said that these vaccines may be illegally smuggled or may come from a pharmaceutical factory in Siping, Jilin.

　　In addition, 32 of them are over the recommended vaccination age of nine-valent HPV vaccine (16-26 years old), that is to say, they do not fully understand the protective effect of HPV vaccine. Why do these older women spend nearly 10,000 yuan chasing the nine-valent HPV vaccine of unknown origin?

　　Many experts told The Paper that we should treat the value of the nine-valent HPV vaccine more rationally and need to cool down the "online celebrity" vaccine.

　　Hainan Boao Yinfeng Kangyang International Hospital, sealed by qionghai city Health and Health Commission on April 29th.A Hard-to-Find Nine-valent HPV Vaccine "Myth"

　　Since it was approved on April 28 last year, the strong demand for nine-valent HPV vaccine has triggered an appointment boom in various places, and Beijing, Shenzhen, Hangzhou, Guangzhou and other places have all experienced the phenomenon of "one needle is hard to find".

　　On April 29th, The Paper called the Hubei Provincial Center for Cervical Cancer Prevention and Treatment, and the outpatient department said that it was normal to make an appointment every Monday on the Internet because "there are only a dozen needles at nine prices every week".

　　In many cities, booking a nine-valent HPV vaccine requires a lottery. For example, in Nanning, Guangxi, after winning the lottery, the applicant will be informed of the specific inoculation place and time. If the inoculation is not completed within the specified time, it will be included in &lsquo; Blacklist &rsquo; You must not participate in the lottery within half a year. "

　　In Shenzhen, from November last year, it was changed from "grab the number to make an appointment" to "shake the number to make an appointment". There were 95,111 valid applicants in the first lottery, and only 1,305 applicants won the lottery, with a winning rate of 1.37%.

　　Behind the "one needle is hard to find" is the publicity upsurge of HPV vaccine that lasted for several years, which even shaped the nine-valent HPV vaccine into a "myth".

　　Since the bivalent HPV vaccine was approved in 2016, titles such as "Ten years waiting, cervical cancer vaccine was finally approved" and "Chinese people waited for ten years, cervical cancer vaccine should not be missed" appeared in the media and occupied the circle of friends.

　　In fact, HPV vaccine has been listed in the United States, Australia and other countries as early as 2006. In 2013, Professor Qiao Youlin from China Academy of Medical Sciences and Institute of Oncology of Peking Union Medical College and his research team published a study in the international authoritative magazine Vaccine, saying that if the cervical cancer vaccine was absent from China for seven years, 380,000 women would miss protection opportunities and become cervical cancer patients in the future if effective intervention measures such as screening were not applied.

　　This research has attracted the attention of the domestic media. Since 2014, there have been reports in China about the long waiting time of cervical cancer vaccine. Until the first HPV vaccine was approved in China in 2016, the listing of tetravalent HPV vaccine in China has also caused widespread concern.

　　Under the ardent expectation of the public, on April 28th last year, the nine-valent HPV vaccine was approved by National Medical Products Administration at "rocket speed". It took only eight days from the acceptance of the marketing application to the conditional approval, setting a new approval record.

　　Who can be vaccinated with nine-valent HPV vaccine? Why is the recommended vaccination age limited to 16-26 years old? How to rationally treat the role of HPV vaccine in preventing cervical cancer? These questions are rarely mentioned.

　　"There is indeed a phenomenon of over-promotion of HPV vaccine. According to the guidance of WHO, it is clear that even if HPV vaccine is vaccinated, cervical cancer cannot be completely avoided." Wang Yuedan, deputy director of the Department of Immunology of Peking University, told The Paper on April 29th.

　　Some experts also pointed out that the frequent reports of vaccine shortage in the media and online have stimulated more women’s desire for vaccination, thus pushing up the market demand and increasing the supply gap.

　　HPV vaccine is only part of the prevention strategy.

　　"Popular Science Questions and Reference Answers about HPV Vaccine" published in National Medical Products Administration official website explained that for most people, being infected with HPV virus is like "getting a cold in the cervix", so there is no need to be too nervous and afraid.

　　"More than 80% of HPV infections will be naturally cleared within 8 months, and only a few persistent high-risk HPV infections can cause cancer for more than 2 years. Among those who continue to be infected, only a few people will develop cervical precancerous lesions, and only a few of the latter will develop into cancer. " Mentioned in the above popular science question and answer.

　　Two experts, Hu Shangying and Qiao Youlin, from the National Cancer Center and Peking Union Medical College Cancer Hospital of China Academy of Medical Sciences, also emphasized that HPV vaccination should be a part of the comprehensive prevention strategy for cervical cancer and other related diseases in a paper "Interpretation of the 2017 WHO HPV vaccine position paper" published in the Chinese journal of preventive medicine. In addition to vaccination, it also includes health education for women to avoid risky behaviors, screening, diagnosis and treatment, training health workers, and improving the accessibility of effective screening and treatment services.

　　For women over the age of 26 who want to get a 9-valent HPV vaccine in China, Liu Fangxun, deputy director of the Department of Special Needs International Medicine of Peking University International Hospital, suggested that they can choose to get a 4-valent HPV vaccine and have a cervical cytology (TCT) examination every year.

　　The best time for HPV vaccination is before sex, that is, before the first exposure to HPV infection. Therefore, teenagers are the best age for HPV vaccination.

　　The recommended vaccination age of bivalent HPV vaccine in China is 9-25 years old women, tetravalent HPV vaccine is suitable for 20-45 years old women, and nonavalent HPV vaccine is suitable for 16-26 years old women.

　　However, the recommended vaccination ages are different in different countries and regions. In the United States, the applicable ages of these three vaccines were all from 9 to 26 when they were first approved. It was not until last October that the indications of the 9-valent HPV vaccine were revised after an average 3.5-year follow-up study targeting 3,200 women aged 27-45. The US FDA approved the application of the 9-valent HPV vaccine to expand the age adaptation range.

　　At present, there is not enough clinical trial data in China to prove that people who are vaccinated with nine-valent HPV vaccine over 26 years old can get the same protective effect as the recommended vaccination age. In Hu Shangying and Qiao Youlin’s aforementioned papers, it is also emphasized that the protective effect of vaccines on older women is lower than that of younger women.

　　On April 28th, 2018, National Medical Products Administration conditionally approved the marketing of nine-valent HPV vaccine for preventing cervical cancer. Unlike bivalent and tetravalent HPV vaccines, the nine-valent HPV vaccine is conditionally approved.

　　Why is it conditionally approved? The nine-valent HPV vaccine is based on the approved data of the previous four-valent HPV vaccine, and it can conditionally accept overseas clinical trial data and bridge with overseas clinical data. Therefore, it is possible to conditionally approve the import registration of products in the shortest time.

　　Among the foreign clinical trials presented in the China instructions of tetravalent HPV vaccine, there is only one phase III trial aimed at the age group of 27-45, and the result is that "the effectiveness of this product in preventing CIN2/3 (cervical precancerous lesion), AIS (adenocarcinoma in situ) or cervical cancer related to HPV16 and 18 in women aged 27-45 has not been confirmed yet".

　　The intermediary chaos caused by huge demand

　　As a group of older women with more purchasing power and spending power, the irrational consumption demand for nine-valent HPV vaccine has also spawned intermediary industries such as "vaccination travel" and overseas vaccination.

　　Tourism websites and medical intermediary companies have launched nine-valent HPV vaccination services in neighboring countries and regions such as South Korea, Singapore, China and Hongkong.

　　In Hong Kong, the upsurge of HPV vaccination due to the "star effect" has also driven the consumption enthusiasm of some mainland women.

　　As early as November 2006, HPV vaccine was approved to be listed in Hong Kong. At the initial stage of listing, public acceptance was not high. According to the data of the Hong Kong Institute of Pharmacists, from November 2006 to 2014, only about 8.85% of women were vaccinated. This situation was reversed in 2015. In 2015, the HPV vaccine subsidy scheme in Hong Kong was fully launched, and eligible people could enjoy the subsidy price as low as HK$ 1,400 per person, with the subsidy rate exceeding 60%.

　　Hongkong also invited many stars to "help out", and G.E.M., Charlene Choi, Ekin Cheng and other stars participated in the production of public service advertisements for many times.

　　Substantial subsidies and celebrity endorsements and publicity have not only greatly increased the number of local vaccinators, but also attracted a large number of mainland women. However, public hospitals in Hong Kong are closed to mainlanders, and this huge consumer group is targeted by many private clinics and intermediaries.

　　In the qualified regular vaccination sites in China, age is a threshold, which blocks this part of the population over 26 years old. Moreover, before the nine-valent HPV vaccine is officially approved in Chinese mainland, it can only be inoculated abroad to get a wider range of titer protection.

　　An endless stream of cross-border vaccinators even once "stopped supplying" the nine-valent HPV vaccine in Hong Kong.

　　The Paper previously reported that from October 12 to December 1, 2017, Merck had directly suspended the supply of nine-valent HPV vaccine in major clinics in Hong Kong, and a large number of mainland consumers who went to Hong Kong for vaccination had disputes with vaccination institutions because of "broken needles".

　　After the unprecedented shortage, the risks of intermediary soliciting customers out of order, no contract documents and difficulties in safeguarding rights are exposed.

　　The age limit is not a problem in many intermediaries. An intermediary who went to Hong Kong to vaccinate the nine-valent HPV vaccine introduced to The Paper: "(Women) can fight if they have menstruation."

　　This chaos is also reflected in the incident of "suspected vaccination of fake nine-valent HPV vaccine" in Yinfeng Hospital.

　　The Paper interviewed 36 female vaccinators in this incident. According to the story, most of the 36 vaccinators were between 20 and 40 years old, and one of them was 49 years old at the time of vaccination. They all recommended each other through acquaintances, paid Wang Lina, who claimed to be the medical staff of Yinfeng Hospital, 900 yuan as the vaccination deposit in advance, and then swiped the card at the involved hospital or transferred 8,100 yuan online, paying a total of 9,000 yuan for the vaccination of this batch of nine-valent HPV vaccines.

　　"9000 yuan should be a random charge." Wang Yuedan said that according to the pricing of domestic nine-valent HPV vaccine, the current price of nine-valent HPV vaccine in the mainland is about 1,300 yuan/needle, and the price of completing three needles is less than 4,000 yuan.

　　In addition to the high premium, there are other risks in vaccination through informal channels in China.

　　According to Hong Kong Ta Kung Pao’s report on April 29th, doctors with unhealthy clinics in Hong Kong, in order to make huge profits, used the genuine nine-valent HPV vaccine produced by Merck Pharmaceutical Factory in the United States to attract mainland customers, and then replaced the genuine nine-valent HPV vaccine with parallel vaccines of unknown origin to vaccinate the guests.

　　"Which institution’s medical staff can fight (over age) means that it is in violation of regulations. If the institution can violate regulations in this place, it may also violate regulations in other links." Liu Fangxun, deputy chief physician of the Special Needs International Medical Department of Peking University International Hospital, told The Paper that vaccine management and cold chain transportation are closely linked in China, which is closely related to the quality and safety of vaccines. Inoculators should choose regular inoculation institutions.

　　Many places have seized HPV vaccine smuggling.

　　In the case of Yinfeng Hospital’s "suspected illegal inoculation of fake vaccines", the source of these nine-valent HPV vaccines became questionable. Victims who had been vaccinated before said, "The vaccines injected in this batch include unknown potions produced by a factory in Siping, Jilin, and smuggled vaccines."

　　At present, Suzhou police have filed a case for investigation. However, the source of the vaccine that is of concern to the outside world has not been disclosed yet.

　　The Paper previously reported that hundreds of people were involved in the vaccine case of Yinfeng Hospital, which was designated by the Ministry of Public Security to supervise the case. Yinfeng Hospital and Qingdao Meibomen House Beauty Information Consulting Co., Ltd. were just one link.

　　According to public reports, cases of illegal entry of "HPV vaccine" have been seized in Shenzhen, Xiamen, Yantai and other places.

　　In May 2017, the airport office of Yantai Inspection and Quarantine Bureau intercepted a number of illegally brought HPV vaccines in the luggage carried by inbound passengers from Taiwan Province.

　　In September 2017, Zhuhai Gongbei Customs officers intercepted two men at the "no declaration channel" at the entry site of Gongbei Port, and found that their suitcases contained a large number of nine-valent vaccines for cervical cancer. This batch of vaccines is placed in three blue heat preservation bags and a transparent sealed bag, some of which are completely boxed and some are in bulk. It is understood that there are more than 220 vaccines in this batch, equivalent to about 130,000 yuan. The passenger concerned failed to provide the vaccine-related approval.

　　In December 2017, the inspection and quarantine staff of Xiamen Airport Inspection and Quarantine Bureau intercepted 201 illegally brought HPV vaccines from the luggage of passengers entering Malaysia.

　　In March 2018, the staff of Shenzhen Huanggang Inspection and Quarantine Bureau seized a group of 45 boxes of nine-valent cervical cancer vaccines brought by passengers at Futian Port, a large number. On-the-spot inspection found that the vaccines were only wrapped in simple plastic bags and packed in backpacks, and no low-temperature cold chain transportation measures were taken, which was easy to degenerate and fail. The passenger said that the vaccine was brought into the country to help people, and it was impossible to explain the source of the vaccine and failed to provide relevant quarantine approval certificates.

　　In November 2018, Xiamen Customs, affiliated to the Airport Customs, intercepted 201 illegally brought HPV (human papillomavirus) vaccines from the luggage of Malaysian inbound passengers, including 150 tetravalent vaccines and 51 nonavalent vaccines. Passengers failed to declare voluntarily and could not provide relevant quarantine certificates.

　　According to the current drug administration law, smuggled vaccines belong to the category of counterfeit drugs.

　　Lawyer Yin Qingli of Beijing Ross Law Firm analyzed that according to Article 39 of China’s Drug Administration Law, if the vaccine comes from abroad, no matter whether it is true or not abroad, as long as there is no import procedure, it can be identified as the scope of counterfeit drugs.

　　In an interview with The Paper, Yin Qingli said that if the "Yinfeng Hospital case" was related to companies and individuals who directly and intentionally violated customs regulations, evaded customs supervision, and transported the vaccines involved in the case in various ways or evaded customs duties, it was not in the form of purchasing by overseas citizens, and there was no special crime of smuggling vaccines and drugs in China, the related companies and individuals might be suspected of committing smuggling in the ordinary sense. If the vaccine in this case is brought to China by an individual through overseas purchasing and used clinically, the so-called overseas purchasing individual should be suspected of selling counterfeit drugs.

　　"Because of the serious harm of counterfeit drugs, on the one hand, it endangers people’s health and life, on the other hand, it also harms the national drug supervision system and market order, so the criminal law makes such a provision. "Yin Qingli explained to The Paper that it is not difficult to see from the above provisions that the crime of producing and selling counterfeit drugs is an act of crime, that is, whether the act of producing and selling counterfeit drugs causes harm to health or not constitutes this crime.

　　Regarding the grey areas where the revised Vaccine Management Law is concerned about whether it can effectively manage vaccine smuggling, a professional who has been engaged in the research of laws and policies related to drug management for a long time told The Paper that in principle, there are special provisions to follow the Vaccine Law, and no provisions are based on the Drug Management Law. "The draft vaccine law has not specifically stipulated the smuggling of vaccines. These incidents will test the integrity of the law." The above personnel said.

Recently, BYD has frequently appeared in the streets in the summer, and there are pictures of cars arriving at the store and transporting them, which seems to be in line with the rumors that it is about to go public. Earlier, BYD sales staff said that BYD Summer will be listed on January 8 next year. The car is positioned as a medium and large plug-in MPV, equipped with zero-gravity seats, car refrigerators, ceiling screens and other comfort configurations, and adopts BYD’s fifth-generation DM hybrid technology. I believe many friends are waiting for this heavy MPV. What brand-new experiences can it give you? Let’s see in detail!

First of all, BYD Summer conveys the solemn visual feeling of the atmosphere and continues the family’s "Dragon Face" design style. The exposed car paint colors are blue, purple and white. The front shield grille is particularly eye-catching, with a lot of chrome decoration. The chrome-plated decorative strip in the center of the top is newly integrated with the "Xia" IP prefix, with the "Dragon beard" design on both sides, and the parallel short-term elements are adopted inside the lamp group, which has a unified style. The ventilation openings on both sides are simple in design to achieve the effect of highlighting the front grille.

The side profile is relatively square, similar to the traditional MPV, and the design is made for space consideration. Silver chrome plating is added to the upper edge of the window and the D-pillar to reduce the dull feeling. Hidden rear side sliding door guide rail, hub and other configurations are equipped. The length, width and height of the new car are 5145/1970/1805 mm, and the wheelbase is 3045 mm. Except for the width of the car body, it is slightly smaller than DM, and the overall size is close to that of Toyota, which is also positioned at home.

The tail design is flat, and the symbolic Chinese knot elements are embedded in the central penetrating taillight, which can realize three-dimensional display, emphasize the sense of science and technology, and keep the lower enclosure in the same color as the body.

Stepping into the car, BYD Xia has a T-shaped layout and a beige stitching interior, which is more eye-catching. The electronic blocking mechanism at the center console has become a remarkable highlight in the car. There are also three large screens that greatly enhance the sense of technology in the car. The suspended central control panel is expected to be equipped with rotation function, and the latest DiLink 150 intelligent cockpit and high-performance cockpit chip will be applied. There are also embedded full LCD instruments and co-pilot entertainment screens on both sides.

The car adopts a "2+2+3" three-row and seven-seat layout, arranges double zero-gravity seats, provides leg rests, and also supports functions such as seat ventilation, heating and massage. It is estimated that high-profile models will be equipped. Car refrigerator, roof screen, folding small table and other configurations have improved the grade of the whole vehicle. Different from D9, BYD has set up many dense physical buttons on the armrest of the seat in summer, which can control the seat function, air conditioning and so on.

BYD Summer takes care of many details, such as the third row. The third row of seats is equipped with three head pillows, which also supports the function of seat ventilation/heating, and also supports one-button electric folding, which can form an almost flat space with the trunk after being laid down. This design has also been well received by home users.

In terms of power system, BYD Summer will be equipped with the 5th generation DM technology, equipped with a DM-i plug-in hybrid system consisting of a 1.5T engine and an electric motor, and the maximum power of the engine is 115kW. In terms of battery life, according to the information published by the Ministry of Industry and Information Technology, the car has declared two kinds of battery packs of 20.39 kWh and 36.628 kWh, and the pure electric cruising range announced by the Ministry of Industry and Information Technology is 80 km and 145 km respectively. In addition, the new car will also be equipped with Yunqi -C intelligent damping body control system, and the whole system comes standard with the "Eye of God" advanced intelligent driving assistance system.

As the first flagship MPV of the brand-new IP "Xia" of Dynasty. com, BYD Xia’s product strength is bright enough, its design continues the design language of Dynasty series, and it is also at the mainstream level in intelligent cockpit and intelligent driving, and the 5th generation DM technology is in town, which has a strong shock to the players at the same level. It is rumored that BYD’s summer price range is 280,000-350,000. If the starting price is around 280,000, the price is somewhat compromised. Do you think this car is attractive?

Editor/Yiran

Recently, Fengyun T9 has become a hot topic in the automobile circle, especially because it is about to release a new model with strong endurance.. The competition of electric vehicles is becoming more and more fierce, and everyone’s demand for how far they can run is also high. This new model has not only been upgraded in the battery and transmission, but also slightly changed in appearance.In this article, I will analyze the situation of this long-life version T9 from many aspects and see its performance in the market..

The appearance of the long-life version is similar to that of the regular version, as if it were just a different label. But if you take a closer look, the new logo is more concise, and the black on the edges and corners is removed, which looks much more pleasing to the eye. This has not changed much, but it reveals the brand’s thoughts. The LOGO that clings to the feeling looks more fashionable and conforms to the current aesthetics.

There is not much change in appearance, but consumers may feel different in their hearts. When picking a car, everyone will pay attention to the appearance of the car, especially the LOGO, as the face of the brand. This new LOGO makes the front of the car look more pleasing to the eye and adds a touch of fresh temperament to Fengyun T9. Such a little change may be able to catch the eyes of young people and help the models to score points in the market competition.

Fengyun T9 Long Life Edition also has a bullish place, which is its 3DHT hybrid special gearbox. The advent of this gearbox proves that Fengyun has taken another step forward in hybrid car technology.According to the latest information, Fengyun T9 is equipped with a 1.5TGDI engine and a 3DHT gearbox. Although this configuration is not the best, people focus on cost performance, which is quite attractive..

With the rapid development of hybrid technology, consumers are also picky about the power system. Fengyun T9′ s 3DHT transmission may not be as powerful as high-end brands, but it is stable and reliable. This technology is a good choice, it is smooth to drive every day, and it is more worry-free and fuel-efficient for long-distance travel.

Fengyun T9 long-life version of the car weighs 70 kilograms more, which is mainly due to the heavy battery. Look at the figures released now, this car is almost 2 tons, which is much heavier than similar cars. Although it is a little heavy, the control may be almost, but the endurance is good.

With a little weight, the battery is bigger and can run farther, which brings good things to our consumers. But this car, Fengyun T9, needs to solve how to keep driving well while it can run longer. When buying, we should not only see how long we can run, but also see how it feels. How to find a balance between these two points, this is a big hurdle that brands have to pass when they fight with other brands.

Now the Fengyun T9 long battery life version has come, catching up with the time when everyone cares about the battery life of electric vehicles.. Although the configuration is not at the top, the price/performance ratio is definitely good. Everyone is quite optimistic about this new version, and many people say they are waiting for it. Then it is coming soon, and the official announcement of this car will definitely attract many people to see it.

Speaking of choosing an electric car, in addition to seeing how far it can run, the price must also be considered.The price of Fengyun T9′ s long-life version is particularly critical, and the market reaction is directly related to the future of this brand.. To engage in new gadgets, brands must carefully consider the market demand and satisfy consumers.

When Fengyun T9 Long Life Edition comes out, we can find that the brand has become smarter and more flexible in the market competition.. They introduce various models step by step, which is to maintain heat and attract attention in the market. This "feeding" can not only add luster to the brand, but also lay a good foundation for the listing of new products.

In the future, Fengyun T9′ s market performance will be affected by various factors, such as opponents’ trends and consumers’ responses. Brands have to adjust their strategies from time to time and follow the market.Looking at the electric vehicle technology getting better and better, the position of Fengyun T9 Long Life Edition in the market can almost be seen clearly..

Do you think Fengyun T9 Long Life Edition can be deus ex in so many competing products? Come to the comment area and talk about your thoughts! By the way, please like and forward this article!

Chengcheng issued a statement saying that it reserves the right to pursue legal action

　　Sina Entertainment News, yesterday (September 27) there were reports that Guo Fucheng, who loves cars like his life, was involved in the "Ferrari fatal car accident" on September 23. It is known that Chengcheng was working in the mainland at the time of the incident. There is evidence to refute the report. Chengcheng, who was innocently involved in the incident, threatened that he would never participate in illegal racing. He directly denounced the report as boring and ridiculous, and its manager, Xiaomei, said she would reserve the right to pursue legal action.

　　City City, which owns a number of luxury sports cars, recently held a concert tour in the mainland and attended the promotion activities of the movie "C + Detective". It was unexpected yesterday that a magazine pointed out that City City participated in the illegal racing on San Tin Road in Lok Ma Chau, Hong Kong on September 23. During this period, he and two drivers used fire extinguishers to rescue people, and also recorded a statement for the case.

　　Chengcheng, who returned to Hong Kong last night after completing all her work, denied the incident, and revealed that she had been doing publicity in the mainland for the past nine days, saying: "The report is extremely boring and ridiculous. I have been in the mainland for the past nine days to hold concerts and promote movies, and I have never participated in illegal racing." Xiaomei, the city manager, admitted frankly that the report has damaged Chengcheng’s reputation, and the incident has been handled by lawyers, and reserves the right to pursue legal action. Asked if he was unhappy about being wronged? Chengcheng said he didn’t feel it: "So boring, I don’t bother to answer. (Feel innocent?) In short, it’s boring." It is known that Chengcheng held his last "Stage Collection Tour Concert" at Pingxiang Stadium in Jiangxi Province on September 22, and took a four-hour bus to the airport to fly to Shanghai the next morning to do publicity, which is enough to prove that he was not involved in the "Ferrari fatal accident".

　　In addition, Chengcheng’s concert in Jiangxi attracted 20,000 fans. Standing on the A-shaped aerial stage, Chengcheng sang Jay Chou’s "Love" while dancing, which fascinated fans. Chengcheng, who will hold a solo concert in Hong Kong in November, said: "I must bring a new concert to the mainland next year. I hope I can sing there wherever there are Chinese people."

Editor in charge: Liu Liyan

　　From April 1, 2022For 16 months,Initial financial disclosure.

　　On the evening of July 26, the full year of 2021, mid-2022 and full year of 2022 were reissued at one timeReport. Data show that the loss in 2021 is about 56.344 billion yuan, the loss in 2022 is 27.664 billion yuan, and the total loss in two years is as high as 84 billion yuan.

　　Hengda automotive insolvent

　　In 2022, Hengda Automobile’s revenue was about 134 million yuan, an increase of 78.71% year-on-year; cumulative losses andThe losses were 98.906 billion yuan and 68.651 billion yuan respectively. Evergrande’s cash and cash equivalents at December 31, 2022 were 220 million yuan.

　　In terms of debt, as of the end of 2022, Hengda Automobile’s total debt was 183.872 billion yuan, and the debt scale after excluding the advance receipt of 3.314 billion yuan was 180.558 billion yuan. In addition, Hengda Automobile involved about 11.626 billion yuan of unliquidated maturing debts, and the group’s overdue commercial tickets accumulated about 18.512 billion yuan. The total assets of Hengda Automobile are 115.22 billion yuan, which is already insolvent.

　　Specifically, in 2022, Hengda Automobile (includingThe turnover of the Automotive Division) was 134 million yuan, an increase of 78.71% year-on-year. The increase in revenue was mainly due to the Group’s commencement of sales of Hengchi 5 models. In July 2022, Hengda Automobile started pre-ordering models, and more than 320 vehicles had been delivered as of the end of the reporting period.

　　Therefore, cars andSales increased from 1.75 million yuan in 2021 to 60.63 million yuan in 2022, including 60.34 million yuan for automobile sales and 290,000 yuan for parts sales. On the other hand, the income generated by providing technical services in 2022 was 40.92 million yuan, of which the income from NEVS providing technical services was 36.75 million yuan, and the income from Japan Research Institute providing technical services was 2.65 million yuan.

　　In addition, Hengda Automobile’s gross profit loss decreased from 170 million yuan in 2021 to 93.86 million yuan in the reporting period, and the gross profit loss also decreased from 227.83% in 2021 to 70.04% in 2022, mainly due to the start of delivery of Hengchi 5 and the beginning of generating revenue for this division. In addition to selling cars, Hengda Automobile also conducted the sale of some residential properties, which will be gradually discontinued.

　　It is worth mentioning that in Evergrande’s 2022 annual report, the company’s auditors shouldIt issued an audit report saying it "does not express an opinion". The reason is that "significant uncertainties related to Evergrande’s continued operation and insufficient appropriate audit credentials for opening balances and comparative information."

　　According to the report released on May 12 this yearHengda Automobile has completed the divestiture of its real estate business and concentrated resources to ensure the development and production of Hengchi series models. Subsequently, on June 20, Hengda Automobile announced that Hengchi 5 had resumed production in May and had delivered more than 1,000 vehicles by the end of May.

　　"Daily reporter checked the official account of Hengchi found that on July 23 this year, Hengchi Automobile revealed the development progress of Hengchi 6 and 7 models. It is reported that Hengchi 6 is positioned as "a cross-border pure electric A + class SUV of trend, sports and technology", and Hengchi 7 is "luxury and comfortable""B-Class", both new models have completed the design freeze.

　　Hengda Automobile says it will continue to ensure the production and delivery of Hengchi 5

　　In fact, even though the situation is not optimistic, Evergrande still seems to have not given up.

　　In this regard, the relevant person in charge of Hengda Automobile said in an interview with the "Daily" reporter that the group will also ensure the continuous and stable production and delivery of Hengchi 5; in the field of marketing, the group will continue to promote the display experience center, sales center and after-sales services center layout, decoration and opening, and further expand sales channels.

　　according toBudget, if Hengda Automobile can seek more than 29 billion yuan in financing, these funds will help Hengda Automobile launch a number of flagship models and eventually achieve mass production. It is worth mentioning that on the night of July 26, when Hengda Automobile disclosed its financial report, it also announced its foreign debtThe latest news.

　　According to the announcement, the agreement arrangement meeting is expected to be held on the following dates: Evergrande Agreement is scheduled for August 23, 2023; Space-based Agreement is scheduled for August 22, 2023; Scenic Agreement is scheduled for August 22, 2023.

　　Previously, three financial reports including 2021, 2022 performance announcements and 2022 interim results announcements have been issued in succession. The financial report shows that China Evergrande has lost more than 812 billion yuan in two years and its total liabilities exceed 2.40 trillion yuan.

　　"Evergrande Automobile and China Evergrande have released consecutive financial reports, just toPrepared. In every announcement, Hengda tried its best to send a signal to the outside world to save the crisis, but due to the credit crisis of Hengda itself, it is basically difficult to find external blood transfusion channels. "Zhang Xiuyang, secretary general of the China Passenger Car Industry Alliance, told reporters that according to regulations, if the trading is suspended for 18 consecutive months, the Hong Kong Stock Exchange can delist it, which means that Hengda has only two months left to resume trading.

Text | Bento finance　Brother Yu

Editor | Wang Jing

Wei Jianjun is about to regain the richest man in the car circle with an IPO of 60 billion yuan, but with Geely’s fifth IPO, Li Shufu will overtake in the corner again.

As of the close of November 24th, Geely Automobile ranked 31st in the market value ranking of global car companies with a market value of HK$ 100.067 billion. In contrast, BYD ranked fourth and Great Wall Motor ranked 14th. Even Wei Lai and LI, the new forces making cars, ranked 21st and 24th respectively.

Although the market value is "tepid", the enthusiasm of Geely brand to embrace the capital market has never subsided. Last year, Volvo Cars was listed on the Stockholm Stock Exchange in Sweden. In June this year, Polar Star Motor was listed on NASDAQ. And Li Shufu’s Yikatong Technology will soon go public in the United States.

Soon, Geely’s fifth IPO will come again-on October 31st, Geely Automobile announced on the Hong Kong Stock Exchange that the company had submitted a proposal to the Stock Exchange in accordance with the 15th application guideline, which suggested splitting Krypton and listing it independently.

Different from the previous low-key financing, as Geely’s "pro-son", he is desperately drawing a "pie" to the capital market.

On November 17, the customized Robotaxi car built by Krypton for Waymo (Google’s autonomous driving company) was officially unveiled in Los Angeles, USA. It is based on the Krypton M-Vision concept car and will be mass-produced in 2024-which means that the Krypton products will land in the United States in 2024.

At this point, Krypton has obtained the cooperation of three American companies, Google, NVIDIA and Mobileye, in the field of autonomous driving. Such a partner lineup, even European and American multinational car companies, is far behind.

R&D bundled American technology companies and products exported to the American market, and the "one-year-old" pole rushed to the IPO.

The first step of krypton is to take a detour. In September, 2020, the joint venture brand of Geely and Volvo, Lingke Auto, officially released the first pure electric luxury coupe concept car-Lingke ZERO concept, which is also the predecessor of the first model of the brand, Jike 001.

Originally, Geely intended to incubate pure electric vehicles within the system of joint venture brand Linke. But in the end, Geely decided to take out the polar list and make a brand-new independent brand. In March, 2021, Geely Automobile and Geely Holding Group jointly invested and established the brand Krypton, with a total investment of RMB 2 billion.

The birth of krypton, the more important task is to make up for Geely’s shortcomings in the new energy vehicle market.

In 2015, Geely announced its aggressive entry into the new energy field and released the "Blue Geely Action Plan". The goal is that by 2020, the sales of new energy vehicles will account for more than 90% of Geely’s overall sales–but the result is that Geely’s new energy vehicles will only account for 5% of the total sales in 2020, and the Blue Geely Action Plan will fail.

Due to the sloppy first time and the late admission time, Krypton is in an obvious backward state in terms of product richness and channel coverage.

At present, only two models, Extreme Krypton 001 and Extreme Krypton 009, are on sale. Not long ago, the cumulative delivery of Krypton 001 just exceeded 55,000 vehicles. In terms of channels, as of the third quarter of 2022, there were only 169 stores. Judging from the volume, the current extreme krypton can only wrestle with the new forces that build cars.

However, the "direct competitor" faced by Krypton is no longer this volume.

Aside from BYD, which can sell 200,000 vehicles a month, GAC Ai ‘an, which competes for the "first share" with Krypton, has long been far ahead in terms of market size. In October, Ai ‘an once again exceeded the monthly sales of 30,000 vehicles. From January to October, the cumulative delivery volume of Ai ‘an was 210,000 vehicles, fulfilling the annual sales target of 200,000 vehicles ahead of schedule.

It is no wonder that the popularity of Ai ‘an in the capital market far exceeds that of Krypton.

On October 20th, GAC Ai ‘an completed the Series A financing of up to 18.294 billion yuan-the largest financing in the field of vehicle in 2022, and the largest single private financing in the domestic new energy vehicle industry in recent years, and 53 investors in a single round of financing also created the largest number of new energy vehicle enterprises.

In terms of valuation, Ai ‘an has created the highest post-investment valuation of domestic unlisted new energy vehicle companies of 103.239 billion yuan. You know, the market value of Guangzhou Automobile Group is only over 100 billion. According to the current sales growth and the launch of new products, it is very likely that Ai ‘an will build another Guangzhou Automobile Group.

Since we can’t compete with sales, we simply gave up the middle and high-end Red Sea market. Directly entered the high-end car market, and tried to convince the capital market with brand power and product power.

The first task of Krypton is indeed to help Geely get rid of the cheap label.

The former "top three independent brands" were Geely, Great Wall Motor and BYD. In the era of fuel vehicles, BYD has the worst market size and revenue capacity.

But now the pattern is completely reversed. In the first half of this year, BYD increased the average bicycle price by 170,000 yuan by relying on the hot sale of high-end new energy vehicles. In the same period, the average selling price of the Great Wall was 121,200 yuan, while the average bicycle price of Geely was only 102,000 yuan-the last of the three independent brands. Even the Guangzhou Automobile Ai ‘an, which started from the network car, broke through the average product price of 180,000 yuan in September.

Krypton 001, the first car of Krypton brand, is positioned as a "luxury hunting coupe". However, the starting price of this car is 299,000 yuan, which is far from the luxury car. Even the high-end car is slightly reluctant-the high-end model defined by the Association must start at more than 300,000 yuan.

Extreme Krypton 001 Source: Extreme Krypton official website

This pricing strategy is mainly for the convenience of Krypton 001 to meet the price threshold requirements of state subsidies, so the minimum model is set below 300,000 yuan. Even with this explanation, the average large order amount of Extreme Krypton 001 is only 336,000 yuan, which is lower than the average bicycle price of 430,000 yuan from Weilai.

When the second car was launched, Krypton did not choose to lower the price in exchange for a larger market scale. Instead, we will continue to launch a higher-priced MPV model, Extreme Krypton 009, with a price range of 499,000-588,000 yuan. The price of nearly 600,000 yuan is an unprecedented height of Geely in its own brand.

However, it is worth noting that the so-called high-end of Krypton 009 is more like a high-end that is forced to help.

Because in the high-end version of Krypton 009, Contemporary Amperex Technology Co., Limited CTP3.0 Kirin battery was first equipped, and the capacity of this battery pack reached an astonishing 140kWh. Even with the low version, the battery pack capacity has reached 116kWh. According to the current cost price of power battery, the cost of battery pack for low version alone is as high as 150,000 yuan, and that for high version is as high as 182,000 yuan, accounting for 30% of the total car price.

Of course, this does not consider the hidden cost behind the initial mass production of Kirin battery.

In fact, putting heavy and expensive batteries on pure electric MPV models is a rather aggressive attempt. Because pure electric MPV, compared with hybrid and fuel vehicles, has the advantage of better space utilization and certain improvement in driving comfort. However, the original MPV has a large space, and the relative space optimization will not be too obvious. The improvement of driving comfort is difficult to quantify and make users feel.

On the contrary, the shortcomings of pure electric MPV models are very obvious, one is the cruising range, and the other is the convenience of recharging. Judging from the existing scheme, Krypton adopts the "old method" of stacking batteries to improve battery life. But a larger capacity battery means a longer charging time.

In the propaganda copy, Krypton only mentioned the charging time of 140kWh battery pack-10% to 80% takes 28 minutes. The 140kWh Kirin battery takes longer. According to the feedback from the previous owners of 100kWh Krypton 001, it takes 2 hours to fill it normally from 0%. The charging time of krypton 009 with larger capacity battery will be a very big problem.

Extreme Krypton 009 Source: Extreme Krypton official website

You know, the MPV is either a leader or a family member. It is obviously an unpleasant thing to wait with them in the charging station for an hour or two. Especially when you are on a high-speed road, you have to grab charging piles with hundreds of thousands of other electric vehicles, which is extremely inconsistent with the luxury positioning.

Of course, the Krypton brand has no intention of taking measures at this stage.

"I still insist on not doing things on the premise of pursuing sales." Jason Lin, vice president of Krypton Intelligent Technology, said in an interview that Krypton is not pursuing pure high-priced cars, but building the best cars in market segments with creative value to satisfy that market. He also said: "to meet the high-end, it is not the amount of money to measure the high-end, but whether you can represent the most important products in that market."

Perhaps Krypton 009 can convince some consumers, but it is difficult to convince the capital market.

The reason why Krypton can go today is entirely due to Geely’s "selfless dedication".

In September, 2020, Geely Automobile delivered the watch in science and technology innovation board, and successfully held the meeting that month. At that time, Geely’s new story to the capital market was the high-end pure electric product line.

However, with the adjustment of policies and the reorganization of Krypton brand, Geely made a major decision-Geely Automobile withdrew its IPO application in science and technology innovation board in June 2021, and announced that the board of directors of Krypton Intelligent Technology had decided to explore different external financing schemes for the sustainable development of Krypton Intelligent Technology.

Last August, an undelivered Krypton received $500 million investment from ecological partners such as Contemporary Amperex Technology Co., Limited, Billie Billie and Intel Capital in the Pre-A round of financing, corresponding to 5.6% of the shares. According to this calculation, the post-investment valuation of Krypton is close to 60 billion yuan.

It is also possible to double the valuation of krypton if we add the delivery results in the past year or so. However, can this brand really be valued at nearly 100 billion?

Theoretically, the valuation reflects each investor’s expectation of the company’s growth. For car companies, raising the valuation is nothing more than doing three things well: sales volume, core technology and brand value.

As far as the core technology is concerned, krypton is far from any imagination at present. In the two intelligent fields, intelligent driving and intelligent cockpit, there is no full-stack self-research capability, but it relies on mature suppliers to complete the push-intelligent driving, which is handed over to Mobileye；, an autonomous driving technology company owned by Intel; The smart cockpit is taken over by Geely’s Yikatong Technology.

For example, Krypton 001′ s intelligent driving system uses two Mobileye EyeQ5H chips, which is said to be equipped with Mobileye’s SuperVision system, which can support point-to-point assisted driving under various road conditions, such as highways, urban trunk roads, rural roads and urban roads.

However, after more than a year of delivery, even the high-speed navigation assisted driving function has not been realized, let alone the urban assisted driving function that will be launched later. In terms of intelligent driving function, Krypton is not only a generation behind Tesla, but also inferior to Geely’s "old rival" Great Wall Motor (Great Wall’s Mimo Zhixing has achieved high-level assisted driving in the city).

Extremely krypton’s partner in intelligent driving, Intel’s Mobileye, is a famous "black factory" in the automobile industry. In the early days, Tesla and Mobileye broke up because the car companies provided by Mobileye were closed black box solutions. Car companies not only could not modify the algorithms, but also could not share vehicle data with Mobileye.

Li Xiang, CEO of LI, who has always been in honest and frank, has publicly announced the reason for stopping cooperation with Mobileye-because it can’t meet the full-stack self-research needs of our intelligent driving (the most important sensing algorithm is the black box). In addition, the ET7 model has been selected and turned to the NVIDIA Orin chip platform with relatively higher "openness", and the development mode of full-stack self-developed software has been adopted.

In order to create a marketing momentum, Krypton announced that it would become the first automobile brand to use NVIDIA Thor chip, and at the same time, self-developed software based on this chip was carried out. (Thor is the latest chip released by NVIDIA this year. As the successor of Orin, the computing power of a single chip has increased by 8 times to an amazing 2000TOPS).

Originally, everyone thought that Extreme Krypton 009 would make a breakthrough in intelligent driving ability, but in fact, it is a ready-made solution from the bottom chip to the software definition. Previously, all kinds of marketing methods were just "painting cakes" again and again.

In terms of smart cockpit, Krypton also chose to "lie flat" in front of suppliers.

The cockpit of Krypton 001 is based on the whole case plan of Yanfeng Visteon. The so-called "full-case scheme" means that Visteon will provide a complete set of hardware and underlying software development completely according to the product definition and requirements of OEM, and complete the final overall integration work. Basically, it is equivalent to what we often call "outsourcing".

However, due to the limitation of research and development cycle and vehicle cost, the early Krypton 001 was inevitably limited in software and hardware architecture and performance. At that time, the most common problem of the first batch of users was that the car was stuck. In desperation, Krypton had to announce that it would replace the 8155 cockpit chip for the owner free of charge.

On the second model, Krypton 009, the whole project of Yanfeng Visteon was abandoned, but the underlying R&D capability of the entire cockpit was also supported by suppliers. Only this time it was replaced by Geely’s cockpit supplier-Yikatong Technology.

Since its inception in 2017, Yikatong’s main business scope is to integrate multimedia information digital entertainment systems for Geely Automobile. The company’s actual controller and ultimate beneficiary are Li Shufu, chairman of Geely Group. At present, almost all of the 12 OEM customers of Yikatong are brands owned by Li Shufu or Geely. For example, Mercedes-Benz, smart, Lotus, and the protagonist of this article-Krypton.

Source: Extreme Krypton official website

In order to cover up the fact that the intelligent cockpit is "not self-developed", Extreme Krypton brand didn’t mention anything about the "brother enterprise" Yikatong Technology when promoting its products.

Of course, there is nothing wrong with the new brand relying on the advantages of shareholders to grow and develop. Cooperation with suppliers can not only greatly reduce R&D investment, but also quickly adjust in the initial trial and error stage. It’s no wonder that Krypton achieved a positive gross profit margin just after it was delivered for more than a year.

An Conghui, CEO of Krypton Intelligent Technology, revealed in an interview that the gross profit margin of Krypton vehicles reached about 5% in the first half of this year. On the basis of delivering 50,000 vehicles in the second half of this year, the gross profit level will be further improved, and the second model, Krypton 009, will have a better gross profit level.

We should know that Wei Xiaoli, a new car-making force, has been "selling one car at a loss" for a long time, and in the end, all of them were listed on the market with blood and ventured ashore. With the continuous improvement of profitability in the past two years, the gross profit margin of "Wei Xiaoli" has gradually changed from negative to positive.

Of course, krypton’s loss was only transferred to Geely. According to the financial report, in the first half of 2022, Geely’s net profit returned to its mother fell by 35% year-on-year to 1.552 billion yuan, the lowest level in five years. Regarding the decline in profits, Geely made it clear that share-based payment and extreme investment have a great impact on profits. In the first half of the year, share-based expenses led to a decrease of 853 million yuan in profits, and extremely bad losses led to a decrease of 406 million yuan in Geely’s profits.

In this way, due to the "outsourcing" of R&D, Krypton’s financial statements will be quite beautiful-this is undoubtedly the biggest bargaining chip for science and technology innovation board. Therefore, among these newly established independent brands, Krypton is not necessarily the one with the strongest technical strength, but it is likely to be the "most profitable" one.

　　　　　　 CCTV News:Some time ago, the police in eight cities, including Pingdingshan, Nanyang and Luohe, Henan Province, received 33 consecutive reports. The computer main control board and monitor of excavators parked on the construction site at night were stolen, and the police in many places in Henan immediately launched a joint investigation.

　　　　　　 Excavator owner: "A computer version and a monitor will cost 80,000 to 90,000 yuan in total. Contact with after-sales needs to be delivered. It is estimated that it will take more than half a month to install it, and the construction period can be tight and the loss can be great. It will cost 40,000 yuan to 50,000 yuan a month."

　　　　　　 The police immediately launched an investigation. The police found that 33 crime scenes were all suburban rivers and remote areas. They had just returned to work and had not had time to install cameras, but there was no theft in the construction site equipped with cameras. The task force collected videos of public places near the crime scene in the province. After a week of repeated combing, a suspicious vehicle caught the attention of the police. The police found that at about 8 pm on March 3, a car was parked on the roadside about 1 km from the crime scene. On March 4, the car left this place at 0: 00, and returned here two hours later. It was not until 7: 00 in the morning that the people in the car got off the bus, opened the trunk and observed the surroundings. At 8: 00, when there were many people and cars on the road, they drove away.

　　　　　　 Feng Jianpo, the captain of the case investigation brigade of the High-tech Branch of Pingdingshan Public Security Bureau, said: "We believe that this car is a major suspect, because a normal person will not sleep in the car, he will stay in a hotel to find a place, and he will not sleep in the car. He just slept there, which is equivalent to two hours of departure at that time in the morning, and his time of going out coincides with the time of this crime."

　　　　　　 Subsequently, the task force collected nearly a thousand bayonet pictures around the incident, and finally determined the license plate number of the car by comparing the information such as the driving track and vehicle characteristics of the suspected vehicle, and finally locked the suspect Xu Mouchang. On March 17, investigators arrested Xu Mouchang in Luohe, Henan Province, and seized 19 excavators’ motherboards, 15 monitors and crime tools. After the trial, Xu Mouchang wandered around eight cities in Henan and stole 33 core parts of excavators, with a case value of more than 2 million yuan. On April 20, Xu Mouchang was detained in criminal detention. According to Xu Mouchang’s confession, the police are tracking and investigating the people involved.

　　Rated power refers to the power of electrical appliances when they work normally. Its value is the rated voltage of the appliance multiplied by the rated current. If the actual power of the electrical appliance is greater than the rated power, the electrical appliance may be damaged; If the actual power is less than the rated power, the electrical appliance may not run.

　　In DC circuit, the product of rated voltage and rated current is the rated power of electrical appliances. Note: p amount =U amount ×I amount

　　Output power of power equipment or input power of energy-consuming equipment under normal operating conditions. Often in "kilowatts". It also refers to the power that the machines produced in the factory can reach when they work normally. That is, the power of a machine. The rated power of the machine is certain, P=Fv, so the force generated by the machine is inversely proportional to the running speed. For example, when a car is driving on a flat asphalt pavement, the traction force F required is smaller, and the speed can be higher; When the road is uneven or uphill, you need a lot of traction, so you must switch to low speed.

Rated power of computer

　　Rated power is the maximum power that the computer radiation eliminator can provide when it works continuously, and the unit is watt (W), or the unit is kilowatt (KW), and 1kW = 1000W. The computer radiation eliminator is used to replace the computer power cord when working, so its rated power must meet the needs of the computer and is the most important parameter of the computer radiation eliminator. Rated power is closely related to rated voltage and working current, which is equal to rated voltage multiplied by working current in principle, so the rated power of computer radiation eliminator is generally between 1000W and 2000W W. Like the working current, the rated power is the maximum power that can be provided in continuous normal work, not that such power is necessary in work. In fact, the power of the computer radiation eliminator at work is far less than this value, which basically depends on the power required by the computer itself, and the power consumed by the computer radiation eliminator itself is very small.

Rated power of power supply

　　Rated power refers to the power that the power supply stably outputs for a long time when the ambient temperature is -5 degrees to 50 degrees and the voltage range is 180 V to 264 V. When testing the power of power supply, manufacturers usually do it at about 50 degrees. The specific method of marking the rated power of the power supply is generally as follows: under the premise of not exceeding the maximum current output by this circuit, gradually reduce its load resistance, and measure its load voltage drop and ripple coefficient at the same time. When the load voltage drop and ripple coefficient exceed the allowable range, record the current value at this time as the maximum working current. Record the maximum working current of each output, and then compare it with the power standard formulated by Intel, so as to determine the rated output power of the power supply. Rated power is the most important standard in power supply. Usually, the power of the power supply generally refers to the rated output power of the power supply. On the nameplate of the power supply, the marked power should be rated power.